ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

MASSACHUSETTS FINANCIAL SERVICES CO /MA/'s Holding History (CIK: 0000912938)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 495,307 Value ($000) $196,959 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 356,529 Value ($000) $162,577 Avg Close $407.20 Range $309.57 - $484.21

Q4 2023

Shares 112,240 Value ($000) $21,484 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 688,228 Value ($000) $121,885 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 672,397 Value ($000) $127,715 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 765,772 Value ($000) $153,399 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 755,542 Value ($000) $179,555 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 535,599 Value ($000) $107,206 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 344,289 Value ($000) $50,215 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 302,743 Value ($000) $49,434 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 1,322,211 Value ($000) $224,221 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 1,365,287 Value ($000) $257,780 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 1,375,143 Value ($000) $233,115 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 1,462,062 Value ($000) $206,429 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 1,763,367 Value ($000) $229,185 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 1,905,390 Value ($000) $277,424 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 1,063,179 Value ($000) $157,467 Avg Close $134.81 Range $98.01 - $158.37

Q3 2016

Shares 78,048 Value ($000) $5,290 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 77,281 Value ($000) $4,288 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 79,978 Value ($000) $5,020 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 78,993 Value ($000) $7,436 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 79,530 Value ($000) $6,391 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 81,002 Value ($000) $9,709,709 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 82,270 Value ($000) $8,590,634 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 79,722 Value ($000) $7,733,034 Avg Close $92.65 Range $72.80 - $111.49

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	495,307	$196,959	$442.56	$387.03 - $495.55
Q3 2025	356,529	$162,577	$407.20	$309.57 - $484.21
Q4 2023	112,240	$21,484	$170.34	$148.10 - $198.00
Q3 2023	688,228	$121,885	$191.12	$168.65 - $218.88
Q2 2023	672,397	$127,715	$198.26	$183.00 - $212.47
Q1 2023	765,772	$153,399	$210.20	$179.19 - $242.39
Q4 2022	755,542	$179,555	$213.29	$181.65 - $242.97
Q3 2022	535,599	$107,206	$190.74	$135.46 - $236.80
Q2 2022	344,289	$50,215	$141.87	$117.58 - $180.35
Q1 2022	302,743	$49,434	$152.35	$125.00 - $174.66
Q4 2021	1,322,211	$224,221	$185.86	$154.82 - $212.00
Q3 2021	1,365,287	$257,780	$187.58	$166.16 - $209.73
Q2 2021	1,375,143	$233,115	$146.46	$125.08 - $177.53
Q1 2021	1,462,062	$206,429	$150.49	$124.00 - $178.41
Q4 2020	1,763,367	$229,185	$133.53	$119.29 - $148.76
Q3 2020	1,905,390	$277,424	$142.10	$119.67 - $167.33
Q2 2020	1,063,179	$157,467	$134.81	$98.01 - $158.37
Q3 2016	78,048	$5,290	$70.55	$53.56 - $80.11
Q2 2016	77,281	$4,288	$63.00	$49.96 - $75.08
Q1 2016	79,978	$5,020	$66.49	$51.51 - $98.00
Q4 2015	78,993	$7,436	$92.72	$71.14 - $110.75
Q3 2015	79,530	$6,391	$111.10	$76.46 - $137.89
Q2 2015	81,002	$9,709,709	$119.50	$98.63 - $140.00
Q1 2015	82,270	$8,590,634	$101.34	$82.06 - $121.93
Q4 2014	79,722	$7,733,034	$92.65	$72.80 - $111.49