ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Invesco Ltd.'s Holding History (CIK: 0000914208)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,165,840 Value ($000) $861,246 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 1,481,842 Value ($000) $675,720 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 1,341,694 Value ($000) $437,513 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 913,792 Value ($000) $246,742 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 558,490 Value ($000) $131,418 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 695,868 Value ($000) $191,385 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 392,841 Value ($000) $95,460 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 178,313 Value ($000) $26,649 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 176,860 Value ($000) $33,853 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 216,569 Value ($000) $38,354 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 390,127 Value ($000) $74,101 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 367,375 Value ($000) $73,593 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 669,849 Value ($000) $159,190 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 737,830 Value ($000) $147,685 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 168,831 Value ($000) $24,625 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 968,755 Value ($000) $158,187 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 890,090 Value ($000) $150,942 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 1,054,172 Value ($000) $199,039 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 1,001,901 Value ($000) $169,841 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 1,216,103 Value ($000) $171,702 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 1,278,242 Value ($000) $166,133 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 1,094,651 Value ($000) $159,380 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 1,124,695 Value ($000) $166,579 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 739,446 Value ($000) $80,488 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 578,130 Value ($000) $66,584 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 543,482 Value ($000) $43,707 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 496,548 Value ($000) $36,030 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 207,234 Value ($000) $19,366 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 17,448 Value ($000) $1,272 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 14,508 Value ($000) $1,270 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 132,870 Value ($000) $13,086 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 55,730 Value ($000) $6,637 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 72,405 Value ($000) $9,199 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 80,878 Value ($000) $9,502 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 29,200 Value ($000) $2,329 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 170,148 Value ($000) $8,720 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 155,433 Value ($000) $5,819 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 113,766 Value ($000) $7,711 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 12,267 Value ($000) $681 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 130,435 Value ($000) $8,188 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 398,001 Value ($000) $37,468 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 533,505 Value ($000) $42,873 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 707,471 Value ($000) $84,805 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 529,747 Value ($000) $55,316 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 528,608 Value ($000) $51,275 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 515,980 Value ($000) $40,298 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 499,402 Value ($000) $31,547 Avg Close $59.44 Range $47.03 - $71.40

Q4 2013

Shares 381 Value ($000) $24 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 56,511 Value ($000) $3,617 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 162,188 Value ($000) $5,028 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,165,840	$861,246	$442.56	$387.03 - $495.55
Q3 2025	1,481,842	$675,720	$407.20	$309.57 - $484.21
Q2 2025	1,341,694	$437,513	$276.71	$205.87 - $327.21
Q1 2025	913,792	$246,742	$257.00	$230.79 - $300.90
Q4 2024	558,490	$131,418	$262.99	$229.86 - $304.39
Q3 2024	695,868	$191,385	$260.36	$231.01 - $287.55
Q2 2024	392,841	$95,460	$157.87	$141.98 - $252.87
Q1 2024	178,313	$26,649	$166.82	$143.52 - $199.38
Q4 2023	176,860	$33,853	$170.34	$148.10 - $198.00
Q3 2023	216,569	$38,354	$191.12	$168.65 - $218.88
Q2 2023	390,127	$74,101	$198.26	$183.00 - $212.47
Q1 2023	367,375	$73,593	$210.20	$179.19 - $242.39
Q4 2022	669,849	$159,190	$213.29	$181.65 - $242.97
Q3 2022	737,830	$147,685	$190.74	$135.46 - $236.80
Q2 2022	168,831	$24,625	$141.87	$117.58 - $180.35
Q1 2022	968,755	$158,187	$152.35	$125.00 - $174.66
Q4 2021	890,090	$150,942	$185.86	$154.82 - $212.00
Q3 2021	1,054,172	$199,039	$187.58	$166.16 - $209.73
Q2 2021	1,001,901	$169,841	$146.46	$125.08 - $177.53
Q1 2021	1,216,103	$171,702	$150.49	$124.00 - $178.41
Q4 2020	1,278,242	$166,133	$133.53	$119.29 - $148.76
Q3 2020	1,094,651	$159,380	$142.10	$119.67 - $167.33
Q2 2020	1,124,695	$166,579	$134.81	$98.01 - $158.37
Q1 2020	739,446	$80,488	$115.43	$84.97 - $134.51
Q4 2019	578,130	$66,584	$99.70	$73.32 - $125.72
Q3 2019	543,482	$43,707	$79.11	$69.11 - $88.00
Q2 2019	496,548	$36,030	$76.72	$65.81 - $96.08
Q1 2019	207,234	$19,366	$83.64	$70.29 - $93.95
Q4 2018	17,448	$1,272	$76.92	$60.27 - $90.00
Q3 2018	14,508	$1,270	$100.59	$86.95 - $124.22
Q2 2018	132,870	$13,086	$99.19	$87.35 - $118.71
Q1 2018	55,730	$6,637	$128.92	$108.13 - $153.99
Q4 2017	72,405	$9,199	$125.65	$111.25 - $147.63
Q3 2017	80,878	$9,502	$85.36	$70.76 - $119.02
Q2 2017	29,200	$2,329	$63.91	$46.90 - $86.92
Q1 2017	170,148	$8,720	$46.22	$35.98 - $60.41
Q4 2016	155,433	$5,819	$41.87	$31.38 - $71.67
Q3 2016	113,766	$7,711	$70.55	$53.56 - $80.11
Q2 2016	12,267	$681	$63.00	$49.96 - $75.08
Q1 2016	130,435	$8,188	$66.49	$51.51 - $98.00
Q4 2015	398,001	$37,468	$92.72	$71.14 - $110.75
Q3 2015	533,505	$42,873	$111.10	$76.46 - $137.89
Q2 2015	707,471	$84,805	$119.50	$98.63 - $140.00
Q1 2015	529,747	$55,316	$101.34	$82.06 - $121.93
Q4 2014	528,608	$51,275	$92.65	$72.80 - $111.49
Q3 2014	515,980	$40,298	$64.51	$51.93 - $79.88
Q2 2014	499,402	$31,547	$59.44	$47.03 - $71.40
Q4 2013	381	$24	$59.65	$48.16 - $67.97
Q3 2013	56,511	$3,617	$49.85	$31.75 - $65.83
Q2 2013	162,188	$5,028	$26.61	$21.60 - $31.79