ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM's Holding History (CIK: 0000938076)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 114,603 Value ($000) $45,572 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 117,226 Value ($000) $53,455 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 127,050 Value ($000) $41,430 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 125,240 Value ($000) $33,817 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 125,240 Value ($000) $29,470 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 129,417 Value ($000) $35,594 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 135,347 Value ($000) $32,889 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 137,022 Value ($000) $27,448 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 135,887 Value ($000) $26,010 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 131,210 Value ($000) $23,237 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 136,560 Value ($000) $25,938 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 137,022 Value ($000) $27,448 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 137,032 Value ($000) $32,566 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 138,792 Value ($000) $27,781 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 138,597 Value ($000) $20,214 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 145,019 Value ($000) $23,680 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 147,993 Value ($000) $25,097 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 150,084 Value ($000) $28,337 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 152,872 Value ($000) $25,915 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 154,776 Value ($000) $21,853 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 160,226 Value ($000) $20,825 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 150,609 Value ($000) $21,929 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 147,639 Value ($000) $21,867 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 144,001 Value ($000) $15,675 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 139,269 Value ($000) $16,040 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 136,483 Value ($000) $10,976 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 133,173 Value ($000) $9,663 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 125,138 Value ($000) $11,694 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 125,688 Value ($000) $9,164 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 119,888 Value ($000) $10,493 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 120,396 Value ($000) $11,858 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 117,826 Value ($000) $14,033 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 116,220 Value ($000) $14,766 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 108,948 Value ($000) $12,800 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 108,708 Value ($000) $8,671 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 106,508 Value ($000) $5,459 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 108,498 Value ($000) $4,062 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 110,929 Value ($000) $7,519 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 112,689 Value ($000) $6,253 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 92,115 Value ($000) $5,782 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 96,885 Value ($000) $9,121 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 101,330 Value ($000) $8,143 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 100,054 Value ($000) $11,993 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 91,395 Value ($000) $9,543 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 93,747 Value ($000) $9,093 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 93,628 Value ($000) $7,312 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 65,412 Value ($000) $4,132 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 50,649 Value ($000) $3,401 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 50,649 Value ($000) $3,258 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 51,545 Value ($000) $3,299 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 51,395 Value ($000) $1,594 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	114,603	$45,572	$442.56	$387.03 - $495.55
Q3 2025	117,226	$53,455	$407.20	$309.57 - $484.21
Q2 2025	127,050	$41,430	$276.71	$205.87 - $327.21
Q1 2025	125,240	$33,817	$257.00	$230.79 - $300.90
Q4 2024	125,240	$29,470	$262.99	$229.86 - $304.39
Q3 2024	129,417	$35,594	$260.36	$231.01 - $287.55
Q2 2024	135,347	$32,889	$157.87	$141.98 - $252.87
Q1 2024	137,022	$27,448	$166.82	$143.52 - $199.38
Q4 2023	135,887	$26,010	$170.34	$148.10 - $198.00
Q3 2023	131,210	$23,237	$191.12	$168.65 - $218.88
Q2 2023	136,560	$25,938	$198.26	$183.00 - $212.47
Q1 2023	137,022	$27,448	$210.20	$179.19 - $242.39
Q4 2022	137,032	$32,566	$213.29	$181.65 - $242.97
Q3 2022	138,792	$27,781	$190.74	$135.46 - $236.80
Q2 2022	138,597	$20,214	$141.87	$117.58 - $180.35
Q1 2022	145,019	$23,680	$152.35	$125.00 - $174.66
Q4 2021	147,993	$25,097	$185.86	$154.82 - $212.00
Q3 2021	150,084	$28,337	$187.58	$166.16 - $209.73
Q2 2021	152,872	$25,915	$146.46	$125.08 - $177.53
Q1 2021	154,776	$21,853	$150.49	$124.00 - $178.41
Q4 2020	160,226	$20,825	$133.53	$119.29 - $148.76
Q3 2020	150,609	$21,929	$142.10	$119.67 - $167.33
Q2 2020	147,639	$21,867	$134.81	$98.01 - $158.37
Q1 2020	144,001	$15,675	$115.43	$84.97 - $134.51
Q4 2019	139,269	$16,040	$99.70	$73.32 - $125.72
Q3 2019	136,483	$10,976	$79.11	$69.11 - $88.00
Q2 2019	133,173	$9,663	$76.72	$65.81 - $96.08
Q1 2019	125,138	$11,694	$83.64	$70.29 - $93.95
Q4 2018	125,688	$9,164	$76.92	$60.27 - $90.00
Q3 2018	119,888	$10,493	$100.59	$86.95 - $124.22
Q2 2018	120,396	$11,858	$99.19	$87.35 - $118.71
Q1 2018	117,826	$14,033	$128.92	$108.13 - $153.99
Q4 2017	116,220	$14,766	$125.65	$111.25 - $147.63
Q3 2017	108,948	$12,800	$85.36	$70.76 - $119.02
Q2 2017	108,708	$8,671	$63.91	$46.90 - $86.92
Q1 2017	106,508	$5,459	$46.22	$35.98 - $60.41
Q4 2016	108,498	$4,062	$41.87	$31.38 - $71.67
Q3 2016	110,929	$7,519	$70.55	$53.56 - $80.11
Q2 2016	112,689	$6,253	$63.00	$49.96 - $75.08
Q1 2016	92,115	$5,782	$66.49	$51.51 - $98.00
Q4 2015	96,885	$9,121	$92.72	$71.14 - $110.75
Q3 2015	101,330	$8,143	$111.10	$76.46 - $137.89
Q2 2015	100,054	$11,993	$119.50	$98.63 - $140.00
Q1 2015	91,395	$9,543	$101.34	$82.06 - $121.93
Q4 2014	93,747	$9,093	$92.65	$72.80 - $111.49
Q3 2014	93,628	$7,312	$64.51	$51.93 - $79.88
Q2 2014	65,412	$4,132	$59.44	$47.03 - $71.40
Q1 2014	50,649	$3,401	$77.42	$60.24 - $112.57
Q4 2013	50,649	$3,258	$59.65	$48.16 - $67.97
Q3 2013	51,545	$3,299	$49.85	$31.75 - $65.83
Q2 2013	51,395	$1,594	$26.61	$21.60 - $31.79