ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

DEUTSCHE BANK AG\'s Holding History (CIK: 0000948046)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 711,975 Value ($000) $283,117 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 606,320 Value ($000) $276,482 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 649,284 Value ($000) $211,725 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 576,993 Value ($000) $155,800 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 556,579 Value ($000) $130,969 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 539,271 Value ($000) $148,316 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 489,118 Value ($000) $118,856 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 507,077 Value ($000) $75,783 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 462,319 Value ($000) $88,492 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 462,856 Value ($000) $81,972 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 486,876 Value ($000) $92,477 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 459,566 Value ($000) $92,060 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 465,053 Value ($000) $110,520 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 253,684 Value ($000) $50,778 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 247,247 Value ($000) $36,061 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 282,110 Value ($000) $46,066 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 274,648 Value ($000) $46,574 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 282,162 Value ($000) $53,275 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 264,843 Value ($000) $44,896 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 258,582 Value ($000) $36,510 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 293,267 Value ($000) $38,117 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 287,506 Value ($000) $41,860 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 286,090 Value ($000) $42,372 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 292,643 Value ($000) $31,854 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 281,220 Value ($000) $32,385 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 655,630 Value ($000) $52,723 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 756,141 Value ($000) $54,862 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 456,281 Value ($000) $42,635 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 200,268 Value ($000) $14,598 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 238,169 Value ($000) $20,843 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 472,697 Value ($000) $46,553 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 446,660 Value ($000) $53,193 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 211,117 Value ($000) $26,819 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 173,450 Value ($000) $20,376 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 192,396 Value ($000) $15,342 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 207,967 Value ($000) $10,656 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 320,988 Value ($000) $12,015 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 396,224 Value ($000) $26,853 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 392,751 Value ($000) $21,790 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 302,695 Value ($000) $18,998 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 266,246 Value ($000) $25,061 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 378,814 Value ($000) $30,437 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 397,473 Value ($000) $47,638 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 281,619 Value ($000) $29,399 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 209,946 Value ($000) $20,363 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 175,045 Value ($000) $13,668 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 168,039 Value ($000) $10,612 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 254,971 Value ($000) $17,116 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 113,756 Value ($000) $7,313 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 166,749 Value ($000) $10,672 Avg Close $49.85 Range $31.75 - $65.83

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	711,975	$283,117	$442.56	$387.03 - $495.55
Q3 2025	606,320	$276,482	$407.20	$309.57 - $484.21
Q2 2025	649,284	$211,725	$276.71	$205.87 - $327.21
Q1 2025	576,993	$155,800	$257.00	$230.79 - $300.90
Q4 2024	556,579	$130,969	$262.99	$229.86 - $304.39
Q3 2024	539,271	$148,316	$260.36	$231.01 - $287.55
Q2 2024	489,118	$118,856	$157.87	$141.98 - $252.87
Q1 2024	507,077	$75,783	$166.82	$143.52 - $199.38
Q4 2023	462,319	$88,492	$170.34	$148.10 - $198.00
Q3 2023	462,856	$81,972	$191.12	$168.65 - $218.88
Q2 2023	486,876	$92,477	$198.26	$183.00 - $212.47
Q1 2023	459,566	$92,060	$210.20	$179.19 - $242.39
Q4 2022	465,053	$110,520	$213.29	$181.65 - $242.97
Q3 2022	253,684	$50,778	$190.74	$135.46 - $236.80
Q2 2022	247,247	$36,061	$141.87	$117.58 - $180.35
Q1 2022	282,110	$46,066	$152.35	$125.00 - $174.66
Q4 2021	274,648	$46,574	$185.86	$154.82 - $212.00
Q3 2021	282,162	$53,275	$187.58	$166.16 - $209.73
Q2 2021	264,843	$44,896	$146.46	$125.08 - $177.53
Q1 2021	258,582	$36,510	$150.49	$124.00 - $178.41
Q4 2020	293,267	$38,117	$133.53	$119.29 - $148.76
Q3 2020	287,506	$41,860	$142.10	$119.67 - $167.33
Q2 2020	286,090	$42,372	$134.81	$98.01 - $158.37
Q1 2020	292,643	$31,854	$115.43	$84.97 - $134.51
Q4 2019	281,220	$32,385	$99.70	$73.32 - $125.72
Q3 2019	655,630	$52,723	$79.11	$69.11 - $88.00
Q2 2019	756,141	$54,862	$76.72	$65.81 - $96.08
Q1 2019	456,281	$42,635	$83.64	$70.29 - $93.95
Q4 2018	200,268	$14,598	$76.92	$60.27 - $90.00
Q3 2018	238,169	$20,843	$100.59	$86.95 - $124.22
Q2 2018	472,697	$46,553	$99.19	$87.35 - $118.71
Q1 2018	446,660	$53,193	$128.92	$108.13 - $153.99
Q4 2017	211,117	$26,819	$125.65	$111.25 - $147.63
Q3 2017	173,450	$20,376	$85.36	$70.76 - $119.02
Q2 2017	192,396	$15,342	$63.91	$46.90 - $86.92
Q1 2017	207,967	$10,656	$46.22	$35.98 - $60.41
Q4 2016	320,988	$12,015	$41.87	$31.38 - $71.67
Q3 2016	396,224	$26,853	$70.55	$53.56 - $80.11
Q2 2016	392,751	$21,790	$63.00	$49.96 - $75.08
Q1 2016	302,695	$18,998	$66.49	$51.51 - $98.00
Q4 2015	266,246	$25,061	$92.72	$71.14 - $110.75
Q3 2015	378,814	$30,437	$111.10	$76.46 - $137.89
Q2 2015	397,473	$47,638	$119.50	$98.63 - $140.00
Q1 2015	281,619	$29,399	$101.34	$82.06 - $121.93
Q4 2014	209,946	$20,363	$92.65	$72.80 - $111.49
Q3 2014	175,045	$13,668	$64.51	$51.93 - $79.88
Q2 2014	168,039	$10,612	$59.44	$47.03 - $71.40
Q1 2014	254,971	$17,116	$77.42	$60.24 - $112.57
Q4 2013	113,756	$7,313	$59.65	$48.16 - $67.97
Q3 2013	166,749	$10,672	$49.85	$31.75 - $65.83