ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

COMMERCE BANK's Holding History (CIK: 0001009076)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 10,533 Value ($000) $4,188 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 4,531 Value ($000) $2,066 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 4,536 Value ($000) $1,479 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 4,557 Value ($000) $1,230 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 4,502 Value ($000) $1,059 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 4,522 Value ($000) $1,244 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 4,617 Value ($000) $1,122 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 4,656 Value ($000) $696 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 4,683 Value ($000) $896 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 4,606 Value ($000) $816 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 4,578 Value ($000) $870 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 4,608 Value ($000) $923 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 4,450 Value ($000) $1,058 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 4,477 Value ($000) $896 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 24,647 Value ($000) $3,595 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 4,358 Value ($000) $712 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 4,258 Value ($000) $722 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 4,237 Value ($000) $800 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 5,841 Value ($000) $990 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 5,788 Value ($000) $817 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 39,586 Value ($000) $5,145 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 34,535 Value ($000) $5,028 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 31,268 Value ($000) $4,631 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 4,480 Value ($000) $488 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 3,090 Value ($000) $356 Avg Close $99.70 Range $73.32 - $125.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	10,533	$4,188	$442.56	$387.03 - $495.55
Q3 2025	4,531	$2,066	$407.20	$309.57 - $484.21
Q2 2025	4,536	$1,479	$276.71	$205.87 - $327.21
Q1 2025	4,557	$1,230	$257.00	$230.79 - $300.90
Q4 2024	4,502	$1,059	$262.99	$229.86 - $304.39
Q3 2024	4,522	$1,244	$260.36	$231.01 - $287.55
Q2 2024	4,617	$1,122	$157.87	$141.98 - $252.87
Q1 2024	4,656	$696	$166.82	$143.52 - $199.38
Q4 2023	4,683	$896	$170.34	$148.10 - $198.00
Q3 2023	4,606	$816	$191.12	$168.65 - $218.88
Q2 2023	4,578	$870	$198.26	$183.00 - $212.47
Q1 2023	4,608	$923	$210.20	$179.19 - $242.39
Q4 2022	4,450	$1,058	$213.29	$181.65 - $242.97
Q3 2022	4,477	$896	$190.74	$135.46 - $236.80
Q2 2022	24,647	$3,595	$141.87	$117.58 - $180.35
Q1 2022	4,358	$712	$152.35	$125.00 - $174.66
Q4 2021	4,258	$722	$185.86	$154.82 - $212.00
Q3 2021	4,237	$800	$187.58	$166.16 - $209.73
Q2 2021	5,841	$990	$146.46	$125.08 - $177.53
Q1 2021	5,788	$817	$150.49	$124.00 - $178.41
Q4 2020	39,586	$5,145	$133.53	$119.29 - $148.76
Q3 2020	34,535	$5,028	$142.10	$119.67 - $167.33
Q2 2020	31,268	$4,631	$134.81	$98.01 - $158.37
Q1 2020	4,480	$488	$115.43	$84.97 - $134.51
Q4 2019	3,090	$356	$99.70	$73.32 - $125.72