ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

GREAT WEST LIFE ASSURANCE CO /CAN/'s Holding History (CIK: 0001046192)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 57,879 Value ($000) $23 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 93,092 Value ($000) $42 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 91,154 Value ($000) $30 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 83,828 Value ($000) $23 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 76,919 Value ($000) $18 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 68,713 Value ($000) $19 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 54,405 Value ($000) $13 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 47,545 Value ($000) $7 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 45,741 Value ($000) $9 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 44,173 Value ($000) $8 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 44,937 Value ($000) $9 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 43,009 Value ($000) $9 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 42,309 Value ($000) $10 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 42,617 Value ($000) $8,509 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 49,984 Value ($000) $7,295 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 62,369 Value ($000) $10,786 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 51,477 Value ($000) $8,706 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 67,216 Value ($000) $12,778 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 70,868 Value ($000) $12,001 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 79,565 Value ($000) $11,163 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 72,520 Value ($000) $9,406 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 60,844 Value ($000) $8,850 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 61,471 Value ($000) $9,063 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 46,089 Value ($000) $5,050 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 46,001 Value ($000) $5,259 Avg Close $99.70 Range $73.32 - $125.72

Q2 2019

Shares 42,171 Value ($000) $3,057 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 52,412 Value ($000) $4,886 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 39,125 Value ($000) $2,734 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 39,280 Value ($000) $3,441 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 48,206 Value ($000) $4,749 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 46,521 Value ($000) $5,549 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 30,362 Value ($000) $3,854 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 8,904 Value ($000) $1,050 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 8,209 Value ($000) $653 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 8,209 Value ($000) $420 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 25,896 Value ($000) $973 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 40,890 Value ($000) $2,768 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 40,890 Value ($000) $2,263 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 40,702 Value ($000) $2,552 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 36,233 Value ($000) $3,413 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 35,994 Value ($000) $2,897 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 11,843 Value ($000) $1,417 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 6,317 Value ($000) $658 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 5,417 Value ($000) $524 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 4,299 Value ($000) $337 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 4,299 Value ($000) $270 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 4,299 Value ($000) $287 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 4,299 Value ($000) $278 Avg Close $59.65 Range $48.16 - $67.97

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	57,879	$23	$442.56	$387.03 - $495.55
Q3 2025	93,092	$42	$407.20	$309.57 - $484.21
Q2 2025	91,154	$30	$276.71	$205.87 - $327.21
Q1 2025	83,828	$23	$257.00	$230.79 - $300.90
Q4 2024	76,919	$18	$262.99	$229.86 - $304.39
Q3 2024	68,713	$19	$260.36	$231.01 - $287.55
Q2 2024	54,405	$13	$157.87	$141.98 - $252.87
Q1 2024	47,545	$7	$166.82	$143.52 - $199.38
Q4 2023	45,741	$9	$170.34	$148.10 - $198.00
Q3 2023	44,173	$8	$191.12	$168.65 - $218.88
Q2 2023	44,937	$9	$198.26	$183.00 - $212.47
Q1 2023	43,009	$9	$210.20	$179.19 - $242.39
Q4 2022	42,309	$10	$213.29	$181.65 - $242.97
Q3 2022	42,617	$8,509	$190.74	$135.46 - $236.80
Q2 2022	49,984	$7,295	$141.87	$117.58 - $180.35
Q1 2022	62,369	$10,786	$152.35	$125.00 - $174.66
Q4 2021	51,477	$8,706	$185.86	$154.82 - $212.00
Q3 2021	67,216	$12,778	$187.58	$166.16 - $209.73
Q2 2021	70,868	$12,001	$146.46	$125.08 - $177.53
Q1 2021	79,565	$11,163	$150.49	$124.00 - $178.41
Q4 2020	72,520	$9,406	$133.53	$119.29 - $148.76
Q3 2020	60,844	$8,850	$142.10	$119.67 - $167.33
Q2 2020	61,471	$9,063	$134.81	$98.01 - $158.37
Q1 2020	46,089	$5,050	$115.43	$84.97 - $134.51
Q4 2019	46,001	$5,259	$99.70	$73.32 - $125.72
Q2 2019	42,171	$3,057	$76.72	$65.81 - $96.08
Q1 2019	52,412	$4,886	$83.64	$70.29 - $93.95
Q4 2018	39,125	$2,734	$76.92	$60.27 - $90.00
Q3 2018	39,280	$3,441	$100.59	$86.95 - $124.22
Q2 2018	48,206	$4,749	$99.19	$87.35 - $118.71
Q1 2018	46,521	$5,549	$128.92	$108.13 - $153.99
Q4 2017	30,362	$3,854	$125.65	$111.25 - $147.63
Q3 2017	8,904	$1,050	$85.36	$70.76 - $119.02
Q2 2017	8,209	$653	$63.91	$46.90 - $86.92
Q1 2017	8,209	$420	$46.22	$35.98 - $60.41
Q4 2016	25,896	$973	$41.87	$31.38 - $71.67
Q3 2016	40,890	$2,768	$70.55	$53.56 - $80.11
Q2 2016	40,890	$2,263	$63.00	$49.96 - $75.08
Q1 2016	40,702	$2,552	$66.49	$51.51 - $98.00
Q4 2015	36,233	$3,413	$92.72	$71.14 - $110.75
Q3 2015	35,994	$2,897	$111.10	$76.46 - $137.89
Q2 2015	11,843	$1,417	$119.50	$98.63 - $140.00
Q1 2015	6,317	$658	$101.34	$82.06 - $121.93
Q4 2014	5,417	$524	$92.65	$72.80 - $111.49
Q3 2014	4,299	$337	$64.51	$51.93 - $79.88
Q2 2014	4,299	$270	$59.44	$47.03 - $71.40
Q1 2014	4,299	$287	$77.42	$60.24 - $112.57
Q4 2013	4,299	$278	$59.65	$48.16 - $67.97