ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

FEDERATED HERMES, INC.'s Holding History (CIK: 0001056288)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 628,063 Value ($000) $249,749 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 550,104 Value ($000) $250,847 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 323,842 Value ($000) $105,602 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 264,173 Value ($000) $71,332 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 249,591 Value ($000) $58,731 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 168,923 Value ($000) $46,459 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 92,608 Value ($000) $22,504 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 148,504 Value ($000) $22,194 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 137,141 Value ($000) $26,250 Avg Close $170.34 Range $148.10 - $198.00

Q2 2023

Shares 4,060 Value ($000) $771 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 46,305 Value ($000) $9,276 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 47,109 Value ($000) $11,195 Avg Close $213.29 Range $181.65 - $242.97

Q4 2021

Shares 992,180 Value ($000) $168,254 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 958,820 Value ($000) $181,035 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 982,078 Value ($000) $166,482 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 988,718 Value ($000) $139,597 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 735,474 Value ($000) $95,589 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 562,911 Value ($000) $81,960 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 576,469 Value ($000) $85,382 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 592,016 Value ($000) $64,441 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 734,362 Value ($000) $84,577 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 555,389 Value ($000) $44,664 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 467,149 Value ($000) $33,896 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 527,151 Value ($000) $49,262 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 526,251 Value ($000) $38,369 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 651,367 Value ($000) $57,007 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 603,250 Value ($000) $59,414 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 401,043 Value ($000) $47,764 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 629,080 Value ($000) $79,924 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 171,167 Value ($000) $20,110 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 62,293 Value ($000) $4,968 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 10,000 Value ($000) $513 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 10,000 Value ($000) $374 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 10,503 Value ($000) $712 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 10,561 Value ($000) $586 Avg Close $63.00 Range $49.96 - $75.08

Q2 2013

Shares 562 Value ($000) $17 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	628,063	$249,749	$442.56	$387.03 - $495.55
Q3 2025	550,104	$250,847	$407.20	$309.57 - $484.21
Q2 2025	323,842	$105,602	$276.71	$205.87 - $327.21
Q1 2025	264,173	$71,332	$257.00	$230.79 - $300.90
Q4 2024	249,591	$58,731	$262.99	$229.86 - $304.39
Q3 2024	168,923	$46,459	$260.36	$231.01 - $287.55
Q2 2024	92,608	$22,504	$157.87	$141.98 - $252.87
Q1 2024	148,504	$22,194	$166.82	$143.52 - $199.38
Q4 2023	137,141	$26,250	$170.34	$148.10 - $198.00
Q2 2023	4,060	$771	$198.26	$183.00 - $212.47
Q1 2023	46,305	$9,276	$210.20	$179.19 - $242.39
Q4 2022	47,109	$11,195	$213.29	$181.65 - $242.97
Q4 2021	992,180	$168,254	$185.86	$154.82 - $212.00
Q3 2021	958,820	$181,035	$187.58	$166.16 - $209.73
Q2 2021	982,078	$166,482	$146.46	$125.08 - $177.53
Q1 2021	988,718	$139,597	$150.49	$124.00 - $178.41
Q4 2020	735,474	$95,589	$133.53	$119.29 - $148.76
Q3 2020	562,911	$81,960	$142.10	$119.67 - $167.33
Q2 2020	576,469	$85,382	$134.81	$98.01 - $158.37
Q1 2020	592,016	$64,441	$115.43	$84.97 - $134.51
Q4 2019	734,362	$84,577	$99.70	$73.32 - $125.72
Q3 2019	555,389	$44,664	$79.11	$69.11 - $88.00
Q2 2019	467,149	$33,896	$76.72	$65.81 - $96.08
Q1 2019	527,151	$49,262	$83.64	$70.29 - $93.95
Q4 2018	526,251	$38,369	$76.92	$60.27 - $90.00
Q3 2018	651,367	$57,007	$100.59	$86.95 - $124.22
Q2 2018	603,250	$59,414	$99.19	$87.35 - $118.71
Q1 2018	401,043	$47,764	$128.92	$108.13 - $153.99
Q4 2017	629,080	$79,924	$125.65	$111.25 - $147.63
Q3 2017	171,167	$20,110	$85.36	$70.76 - $119.02
Q2 2017	62,293	$4,968	$63.91	$46.90 - $86.92
Q1 2017	10,000	$513	$46.22	$35.98 - $60.41
Q4 2016	10,000	$374	$41.87	$31.38 - $71.67
Q3 2016	10,503	$712	$70.55	$53.56 - $80.11
Q2 2016	10,561	$586	$63.00	$49.96 - $75.08
Q2 2013	562	$17	$26.61	$21.60 - $31.79