ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

ALLIANCEBERNSTEIN L.P.'s Holding History (CIK: 0001109448)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 44,319 Value ($000) $17,623 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 43,776 Value ($000) $19,962 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 67,131 Value ($000) $21,891 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 44,837 Value ($000) $12,107 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 44,590 Value ($000) $10,492 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 52,624 Value ($000) $14,473 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 45,373 Value ($000) $11,026 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 54,176 Value ($000) $8,097 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 520,839 Value ($000) $99,694 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 540,706 Value ($000) $95,759 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 550,279 Value ($000) $104,520 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 535,959 Value ($000) $107,363 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 71,184 Value ($000) $16,917 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 74,968 Value ($000) $15,006 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 675,007 Value ($000) $98,450 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 56,537 Value ($000) $9,232 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 69,880 Value ($000) $11,850 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 66,686 Value ($000) $12,591 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 61,921 Value ($000) $10,497 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 67,719 Value ($000) $9,561 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 123,477 Value ($000) $16,048 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 66,790 Value ($000) $9,725 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 77,691 Value ($000) $11,507 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 73,201 Value ($000) $7,968 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 127,788 Value ($000) $14,717 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 115,143 Value ($000) $9,260 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 103,871 Value ($000) $7,537 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 48,791 Value ($000) $4,560 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 48,990 Value ($000) $3,572 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 49,688 Value ($000) $4,349 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 51,328 Value ($000) $5,055 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 49,283 Value ($000) $5,870 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 45,453 Value ($000) $5,775 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 43,773 Value ($000) $5,143 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 47,873 Value ($000) $3,818 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 47,475 Value ($000) $2,433 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 47,805 Value ($000) $1,790 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 50,064 Value ($000) $3,393 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 50,214 Value ($000) $2,786 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 49,614 Value ($000) $3,114 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 49,939 Value ($000) $4,701 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 51,124 Value ($000) $4,108 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 51,985 Value ($000) $6,231 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 48,508 Value ($000) $5,065 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 45,538 Value ($000) $4,417 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 41,638 Value ($000) $3,252 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 41,138 Value ($000) $2,599 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 115,950 Value ($000) $7,785 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 121,376 Value ($000) $7,808 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 123,348 Value ($000) $7,896 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 123,190 Value ($000) $3,820 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	44,319	$17,623	$442.56	$387.03 - $495.55
Q3 2025	43,776	$19,962	$407.20	$309.57 - $484.21
Q2 2025	67,131	$21,891	$276.71	$205.87 - $327.21
Q1 2025	44,837	$12,107	$257.00	$230.79 - $300.90
Q4 2024	44,590	$10,492	$262.99	$229.86 - $304.39
Q3 2024	52,624	$14,473	$260.36	$231.01 - $287.55
Q2 2024	45,373	$11,026	$157.87	$141.98 - $252.87
Q1 2024	54,176	$8,097	$166.82	$143.52 - $199.38
Q4 2023	520,839	$99,694	$170.34	$148.10 - $198.00
Q3 2023	540,706	$95,759	$191.12	$168.65 - $218.88
Q2 2023	550,279	$104,520	$198.26	$183.00 - $212.47
Q1 2023	535,959	$107,363	$210.20	$179.19 - $242.39
Q4 2022	71,184	$16,917	$213.29	$181.65 - $242.97
Q3 2022	74,968	$15,006	$190.74	$135.46 - $236.80
Q2 2022	675,007	$98,450	$141.87	$117.58 - $180.35
Q1 2022	56,537	$9,232	$152.35	$125.00 - $174.66
Q4 2021	69,880	$11,850	$185.86	$154.82 - $212.00
Q3 2021	66,686	$12,591	$187.58	$166.16 - $209.73
Q2 2021	61,921	$10,497	$146.46	$125.08 - $177.53
Q1 2021	67,719	$9,561	$150.49	$124.00 - $178.41
Q4 2020	123,477	$16,048	$133.53	$119.29 - $148.76
Q3 2020	66,790	$9,725	$142.10	$119.67 - $167.33
Q2 2020	77,691	$11,507	$134.81	$98.01 - $158.37
Q1 2020	73,201	$7,968	$115.43	$84.97 - $134.51
Q4 2019	127,788	$14,717	$99.70	$73.32 - $125.72
Q3 2019	115,143	$9,260	$79.11	$69.11 - $88.00
Q2 2019	103,871	$7,537	$76.72	$65.81 - $96.08
Q1 2019	48,791	$4,560	$83.64	$70.29 - $93.95
Q4 2018	48,990	$3,572	$76.92	$60.27 - $90.00
Q3 2018	49,688	$4,349	$100.59	$86.95 - $124.22
Q2 2018	51,328	$5,055	$99.19	$87.35 - $118.71
Q1 2018	49,283	$5,870	$128.92	$108.13 - $153.99
Q4 2017	45,453	$5,775	$125.65	$111.25 - $147.63
Q3 2017	43,773	$5,143	$85.36	$70.76 - $119.02
Q2 2017	47,873	$3,818	$63.91	$46.90 - $86.92
Q1 2017	47,475	$2,433	$46.22	$35.98 - $60.41
Q4 2016	47,805	$1,790	$41.87	$31.38 - $71.67
Q3 2016	50,064	$3,393	$70.55	$53.56 - $80.11
Q2 2016	50,214	$2,786	$63.00	$49.96 - $75.08
Q1 2016	49,614	$3,114	$66.49	$51.51 - $98.00
Q4 2015	49,939	$4,701	$92.72	$71.14 - $110.75
Q3 2015	51,124	$4,108	$111.10	$76.46 - $137.89
Q2 2015	51,985	$6,231	$119.50	$98.63 - $140.00
Q1 2015	48,508	$5,065	$101.34	$82.06 - $121.93
Q4 2014	45,538	$4,417	$92.65	$72.80 - $111.49
Q3 2014	41,638	$3,252	$64.51	$51.93 - $79.88
Q2 2014	41,138	$2,599	$59.44	$47.03 - $71.40
Q1 2014	115,950	$7,785	$77.42	$60.24 - $112.57
Q4 2013	121,376	$7,808	$59.65	$48.16 - $67.97
Q3 2013	123,348	$7,896	$49.85	$31.75 - $65.83
Q2 2013	123,190	$3,820	$26.61	$21.60 - $31.79