ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

PRINCIPAL FINANCIAL GROUP INC's Holding History (CIK: 0001126328)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 3,498 Value ($000) $1,391 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 5,420 Value ($000) $2,472 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 50,534 Value ($000) $16,479 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 34,701 Value ($000) $9,370 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 10,378 Value ($000) $2,442 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 10,608 Value ($000) $2,918 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 14,189 Value ($000) $3,448 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 19,356 Value ($000) $2,893 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 19,629 Value ($000) $3,757 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 22,505 Value ($000) $3,986 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 21,662 Value ($000) $4,114 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 20,984 Value ($000) $4,204 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 23,963 Value ($000) $5,695 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 26,445 Value ($000) $5,293 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 31,528 Value ($000) $4,598 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 28,465 Value ($000) $4,648 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 30,022 Value ($000) $5,092 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 38,640 Value ($000) $7,296 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 42,935 Value ($000) $7,278 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 40,080 Value ($000) $5,659 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 38,066 Value ($000) $4,947 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 33,165 Value ($000) $4,828 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 36,191 Value ($000) $5,360 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 28,917 Value ($000) $3,147 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 27,439 Value ($000) $3,160 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 27,532 Value ($000) $2,214 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 28,567 Value ($000) $2,073 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 25,633 Value ($000) $2,396 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 23,845 Value ($000) $1,739 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 25,182 Value ($000) $2,204 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 24,289 Value ($000) $2,392 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 24,525 Value ($000) $2,921 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 23,262 Value ($000) $2,955 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 13,199 Value ($000) $1,551 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 15,256 Value ($000) $1,217 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 12,328 Value ($000) $632 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 12,851 Value ($000) $481 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 15,117 Value ($000) $1,025 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 15,152 Value ($000) $841 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 13,391 Value ($000) $841 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 13,468 Value ($000) $1,268 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 13,447 Value ($000) $1,081 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 7,449 Value ($000) $893 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 4,497 Value ($000) $470 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 5,218 Value ($000) $506 Avg Close $92.65 Range $72.80 - $111.49

Q2 2014

Shares 30,604 Value ($000) $1,933 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 76,424 Value ($000) $5,132 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 76,600 Value ($000) $4,928 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 72,348 Value ($000) $4,632 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 16,995 Value ($000) $527 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	3,498	$1,391	$442.56	$387.03 - $495.55
Q3 2025	5,420	$2,472	$407.20	$309.57 - $484.21
Q2 2025	50,534	$16,479	$276.71	$205.87 - $327.21
Q1 2025	34,701	$9,370	$257.00	$230.79 - $300.90
Q4 2024	10,378	$2,442	$262.99	$229.86 - $304.39
Q3 2024	10,608	$2,918	$260.36	$231.01 - $287.55
Q2 2024	14,189	$3,448	$157.87	$141.98 - $252.87
Q1 2024	19,356	$2,893	$166.82	$143.52 - $199.38
Q4 2023	19,629	$3,757	$170.34	$148.10 - $198.00
Q3 2023	22,505	$3,986	$191.12	$168.65 - $218.88
Q2 2023	21,662	$4,114	$198.26	$183.00 - $212.47
Q1 2023	20,984	$4,204	$210.20	$179.19 - $242.39
Q4 2022	23,963	$5,695	$213.29	$181.65 - $242.97
Q3 2022	26,445	$5,293	$190.74	$135.46 - $236.80
Q2 2022	31,528	$4,598	$141.87	$117.58 - $180.35
Q1 2022	28,465	$4,648	$152.35	$125.00 - $174.66
Q4 2021	30,022	$5,092	$185.86	$154.82 - $212.00
Q3 2021	38,640	$7,296	$187.58	$166.16 - $209.73
Q2 2021	42,935	$7,278	$146.46	$125.08 - $177.53
Q1 2021	40,080	$5,659	$150.49	$124.00 - $178.41
Q4 2020	38,066	$4,947	$133.53	$119.29 - $148.76
Q3 2020	33,165	$4,828	$142.10	$119.67 - $167.33
Q2 2020	36,191	$5,360	$134.81	$98.01 - $158.37
Q1 2020	28,917	$3,147	$115.43	$84.97 - $134.51
Q4 2019	27,439	$3,160	$99.70	$73.32 - $125.72
Q3 2019	27,532	$2,214	$79.11	$69.11 - $88.00
Q2 2019	28,567	$2,073	$76.72	$65.81 - $96.08
Q1 2019	25,633	$2,396	$83.64	$70.29 - $93.95
Q4 2018	23,845	$1,739	$76.92	$60.27 - $90.00
Q3 2018	25,182	$2,204	$100.59	$86.95 - $124.22
Q2 2018	24,289	$2,392	$99.19	$87.35 - $118.71
Q1 2018	24,525	$2,921	$128.92	$108.13 - $153.99
Q4 2017	23,262	$2,955	$125.65	$111.25 - $147.63
Q3 2017	13,199	$1,551	$85.36	$70.76 - $119.02
Q2 2017	15,256	$1,217	$63.91	$46.90 - $86.92
Q1 2017	12,328	$632	$46.22	$35.98 - $60.41
Q4 2016	12,851	$481	$41.87	$31.38 - $71.67
Q3 2016	15,117	$1,025	$70.55	$53.56 - $80.11
Q2 2016	15,152	$841	$63.00	$49.96 - $75.08
Q1 2016	13,391	$841	$66.49	$51.51 - $98.00
Q4 2015	13,468	$1,268	$92.72	$71.14 - $110.75
Q3 2015	13,447	$1,081	$111.10	$76.46 - $137.89
Q2 2015	7,449	$893	$119.50	$98.63 - $140.00
Q1 2015	4,497	$470	$101.34	$82.06 - $121.93
Q4 2014	5,218	$506	$92.65	$72.80 - $111.49
Q2 2014	30,604	$1,933	$59.44	$47.03 - $71.40
Q1 2014	76,424	$5,132	$77.42	$60.24 - $112.57
Q4 2013	76,600	$4,928	$59.65	$48.16 - $67.97
Q3 2013	72,348	$4,632	$49.85	$31.75 - $65.83
Q2 2013	16,995	$527	$26.61	$21.60 - $31.79