ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

LOS ANGELES CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001177206)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 240,052 Value ($000) $107,918 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 159,394 Value ($000) $72,684 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 67,399 Value ($000) $21,978 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 80,862 Value ($000) $21,834 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 94,822 Value ($000) $22,313 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 137,017 Value ($000) $37,684 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 1,188 Value ($000) $289 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 2,959 Value ($000) $442 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 17,028 Value ($000) $3,259 Avg Close $170.34 Range $148.10 - $198.00

Q2 2023

Shares 1,507 Value ($000) $286 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 1,507 Value ($000) $302 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 2,067 Value ($000) $491 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 6,112 Value ($000) $1,223 Avg Close $190.74 Range $135.46 - $236.80

Q3 2019

Shares 4,081 Value ($000) $328 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 5,121 Value ($000) $372 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 49,445 Value ($000) $4,621 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 49,835 Value ($000) $3,633 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 147,103 Value ($000) $12,874 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 302,695 Value ($000) $29,812 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 69,913 Value ($000) $8,327 Avg Close $128.92 Range $108.13 - $153.99

Q3 2016

Shares 161,415 Value ($000) $10,941 Avg Close $70.55 Range $53.56 - $80.11

Q4 2015

Shares 13,255 Value ($000) $1,248 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 15,260 Value ($000) $1,226 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 21,232 Value ($000) $2,545 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 163,057 Value ($000) $17,026 Avg Close $101.34 Range $82.06 - $121.93

Q1 2014

Shares 16,785 Value ($000) $1,127 Avg Close $77.42 Range $60.24 - $112.57

Q3 2013

Shares 3,955 Value ($000) $253 Avg Close $49.85 Range $31.75 - $65.83

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	240,052	$107,918	$442.56	$387.03 - $495.55
Q3 2025	159,394	$72,684	$407.20	$309.57 - $484.21
Q2 2025	67,399	$21,978	$276.71	$205.87 - $327.21
Q1 2025	80,862	$21,834	$257.00	$230.79 - $300.90
Q4 2024	94,822	$22,313	$262.99	$229.86 - $304.39
Q3 2024	137,017	$37,684	$260.36	$231.01 - $287.55
Q2 2024	1,188	$289	$157.87	$141.98 - $252.87
Q1 2024	2,959	$442	$166.82	$143.52 - $199.38
Q4 2023	17,028	$3,259	$170.34	$148.10 - $198.00
Q2 2023	1,507	$286	$198.26	$183.00 - $212.47
Q1 2023	1,507	$302	$210.20	$179.19 - $242.39
Q4 2022	2,067	$491	$213.29	$181.65 - $242.97
Q3 2022	6,112	$1,223	$190.74	$135.46 - $236.80
Q3 2019	4,081	$328	$79.11	$69.11 - $88.00
Q2 2019	5,121	$372	$76.72	$65.81 - $96.08
Q1 2019	49,445	$4,621	$83.64	$70.29 - $93.95
Q4 2018	49,835	$3,633	$76.92	$60.27 - $90.00
Q3 2018	147,103	$12,874	$100.59	$86.95 - $124.22
Q2 2018	302,695	$29,812	$99.19	$87.35 - $118.71
Q1 2018	69,913	$8,327	$128.92	$108.13 - $153.99
Q3 2016	161,415	$10,941	$70.55	$53.56 - $80.11
Q4 2015	13,255	$1,248	$92.72	$71.14 - $110.75
Q3 2015	15,260	$1,226	$111.10	$76.46 - $137.89
Q2 2015	21,232	$2,545	$119.50	$98.63 - $140.00
Q1 2015	163,057	$17,026	$101.34	$82.06 - $121.93
Q1 2014	16,785	$1,127	$77.42	$60.24 - $112.57
Q3 2013	3,955	$253	$49.85	$31.75 - $65.83