ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

CIBC Private Wealth Group, LLC's Holding History (CIK: 0001298088)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 200,425 Value ($000) $79,699 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 214,213 Value ($000) $97,681 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 218,329 Value ($000) $71,195 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 205,511 Value ($000) $46,100 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 203,368 Value ($000) $48,920 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 208,486 Value ($000) $57,340 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 206,391 Value ($000) $52,652 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 174,249 Value ($000) $26,718 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 173,701 Value ($000) $33,248 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 174,130 Value ($000) $30,838 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 174,512 Value ($000) $33,147 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 120,981 Value ($000) $24,235 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 121,866 Value ($000) $28,585 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 119,408 Value ($000) $23,901 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 116,242 Value ($000) $16,953 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 120,277 Value ($000) $19,640 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 118,252 Value ($000) $20,052 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 119,145 Value ($000) $22,494 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 118,716 Value ($000) $20,126 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 126,260 Value ($000) $17,827 Avg Close $150.49 Range $124.00 - $178.41

Q1 2018

Shares 5 Value ($000) $1 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 7,555 Value ($000) $960 Avg Close $125.65 Range $111.25 - $147.63

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	200,425	$79,699	$442.56	$387.03 - $495.55
Q3 2025	214,213	$97,681	$407.20	$309.57 - $484.21
Q2 2025	218,329	$71,195	$276.71	$205.87 - $327.21
Q1 2025	205,511	$46,100	$257.00	$230.79 - $300.90
Q4 2024	203,368	$48,920	$262.99	$229.86 - $304.39
Q3 2024	208,486	$57,340	$260.36	$231.01 - $287.55
Q2 2024	206,391	$52,652	$157.87	$141.98 - $252.87
Q1 2024	174,249	$26,718	$166.82	$143.52 - $199.38
Q4 2023	173,701	$33,248	$170.34	$148.10 - $198.00
Q3 2023	174,130	$30,838	$191.12	$168.65 - $218.88
Q2 2023	174,512	$33,147	$198.26	$183.00 - $212.47
Q1 2023	120,981	$24,235	$210.20	$179.19 - $242.39
Q4 2022	121,866	$28,585	$213.29	$181.65 - $242.97
Q3 2022	119,408	$23,901	$190.74	$135.46 - $236.80
Q2 2022	116,242	$16,953	$141.87	$117.58 - $180.35
Q1 2022	120,277	$19,640	$152.35	$125.00 - $174.66
Q4 2021	118,252	$20,052	$185.86	$154.82 - $212.00
Q3 2021	119,145	$22,494	$187.58	$166.16 - $209.73
Q2 2021	118,716	$20,126	$146.46	$125.08 - $177.53
Q1 2021	126,260	$17,827	$150.49	$124.00 - $178.41
Q1 2018	5	$1	$128.92	$108.13 - $153.99
Q4 2017	7,555	$960	$125.65	$111.25 - $147.63