ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Palo Alto Investors LP's Holding History (CIK: 0001306923)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 32,320 Value ($000) $14,738 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 75,535 Value ($000) $24,631 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 83,488 Value ($000) $22,543 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 140,681 Value ($000) $33,104 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 140,681 Value ($000) $38,691 Avg Close $260.36 Range $231.01 - $287.55

Q1 2024

Shares 182,766 Value ($000) $27,314 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 154,437 Value ($000) $29,561 Avg Close $170.34 Range $148.10 - $198.00

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	32,320	$14,738	$407.20	$309.57 - $484.21
Q2 2025	75,535	$24,631	$276.71	$205.87 - $327.21
Q1 2025	83,488	$22,543	$257.00	$230.79 - $300.90
Q4 2024	140,681	$33,104	$262.99	$229.86 - $304.39
Q3 2024	140,681	$38,691	$260.36	$231.01 - $287.55
Q1 2024	182,766	$27,314	$166.82	$143.52 - $199.38
Q4 2023	154,437	$29,561	$170.34	$148.10 - $198.00