ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Clearbridge Investments, LLC's Holding History (CIK: 0001348883)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 597,013 Value ($000) $237,402 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 622,435 Value ($000) $283,830 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 557,099 Value ($000) $181,664 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 7,777 Value ($000) $2,100 Avg Close $257.00 Range $230.79 - $300.90

Q2 2023

Shares 83,185 Value ($000) $15,800 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 76,274 Value ($000) $15,279 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 56,660 Value ($000) $13,465 Avg Close $213.29 Range $181.65 - $242.97

Q2 2020

Shares 365 Value ($000) $54 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 365 Value ($000) $40 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 377 Value ($000) $44 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 377 Value ($000) $30 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 377 Value ($000) $27 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 377 Value ($000) $35 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 377 Value ($000) $27 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 377 Value ($000) $33 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 377 Value ($000) $37 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 2,122 Value ($000) $253 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 2,516 Value ($000) $320 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 4,018 Value ($000) $472 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 4,237 Value ($000) $338 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 1,103 Value ($000) $57 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 1,103 Value ($000) $41 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 1,085 Value ($000) $74 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 594 Value ($000) $33 Avg Close $63.00 Range $49.96 - $75.08

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	597,013	$237,402	$442.56	$387.03 - $495.55
Q3 2025	622,435	$283,830	$407.20	$309.57 - $484.21
Q2 2025	557,099	$181,664	$276.71	$205.87 - $327.21
Q1 2025	7,777	$2,100	$257.00	$230.79 - $300.90
Q2 2023	83,185	$15,800	$198.26	$183.00 - $212.47
Q1 2023	76,274	$15,279	$210.20	$179.19 - $242.39
Q4 2022	56,660	$13,465	$213.29	$181.65 - $242.97
Q2 2020	365	$54	$134.81	$98.01 - $158.37
Q1 2020	365	$40	$115.43	$84.97 - $134.51
Q4 2019	377	$44	$99.70	$73.32 - $125.72
Q3 2019	377	$30	$79.11	$69.11 - $88.00
Q2 2019	377	$27	$76.72	$65.81 - $96.08
Q1 2019	377	$35	$83.64	$70.29 - $93.95
Q4 2018	377	$27	$76.92	$60.27 - $90.00
Q3 2018	377	$33	$100.59	$86.95 - $124.22
Q2 2018	377	$37	$99.19	$87.35 - $118.71
Q1 2018	2,122	$253	$128.92	$108.13 - $153.99
Q4 2017	2,516	$320	$125.65	$111.25 - $147.63
Q3 2017	4,018	$472	$85.36	$70.76 - $119.02
Q2 2017	4,237	$338	$63.91	$46.90 - $86.92
Q1 2017	1,103	$57	$46.22	$35.98 - $60.41
Q4 2016	1,103	$41	$41.87	$31.38 - $71.67
Q3 2016	1,085	$74	$70.55	$53.56 - $80.11
Q2 2016	594	$33	$63.00	$49.96 - $75.08