ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

ProShare Advisors LLC's Holding History (CIK: 0001357955)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 211,077 Value ($000) $83,935 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 4,631 Value ($000) $2,112 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 4,241 Value ($000) $1,383 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 5,840 Value ($000) $1,577 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 6,110 Value ($000) $1,438 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 7,586 Value ($000) $2,086 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 7,809 Value ($000) $1,898 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 8,827 Value ($000) $1,319 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 8,018 Value ($000) $1,535 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 8,172 Value ($000) $1,447 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 8,057 Value ($000) $1,530 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 8,814 Value ($000) $1,766 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 12,041 Value ($000) $2,862 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 12,008 Value ($000) $2,404 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 11,389 Value ($000) $1,661 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 15,190 Value ($000) $2,481 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 19,846 Value ($000) $3,365 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 28,207 Value ($000) $5,326 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 25,369 Value ($000) $4,301 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 18,386 Value ($000) $2,596 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 20,017 Value ($000) $2,602 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 20,694 Value ($000) $3,013 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 20,172 Value ($000) $2,988 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 17,389 Value ($000) $1,893 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 26,775 Value ($000) $3,084 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 32,719 Value ($000) $2,631 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 33,396 Value ($000) $2,423 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 39,919 Value ($000) $3,730 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 36,887 Value ($000) $2,689 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 44,214 Value ($000) $3,870 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 44,233 Value ($000) $4,357 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 48,265 Value ($000) $5,748 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 55,630 Value ($000) $7,068 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 53,478 Value ($000) $6,283 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 48,505 Value ($000) $3,869 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 47,427 Value ($000) $2,431 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 57,713 Value ($000) $2,161 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 56,206 Value ($000) $3,810 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 66,151 Value ($000) $3,671 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 64,623 Value ($000) $4,056 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 70,904 Value ($000) $6,675 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 67,222 Value ($000) $5,402 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 71,340 Value ($000) $8,552 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 71,269 Value ($000) $7,442 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 54,541 Value ($000) $5,290 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 41,789 Value ($000) $3,264 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 48,693 Value ($000) $3,076 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 109,698 Value ($000) $7,365 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 33,864 Value ($000) $2,178 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 60,223 Value ($000) $3,855 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 47,671 Value ($000) $1,478 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	211,077	$83,935	$442.56	$387.03 - $495.55
Q3 2025	4,631	$2,112	$407.20	$309.57 - $484.21
Q2 2025	4,241	$1,383	$276.71	$205.87 - $327.21
Q1 2025	5,840	$1,577	$257.00	$230.79 - $300.90
Q4 2024	6,110	$1,438	$262.99	$229.86 - $304.39
Q3 2024	7,586	$2,086	$260.36	$231.01 - $287.55
Q2 2024	7,809	$1,898	$157.87	$141.98 - $252.87
Q1 2024	8,827	$1,319	$166.82	$143.52 - $199.38
Q4 2023	8,018	$1,535	$170.34	$148.10 - $198.00
Q3 2023	8,172	$1,447	$191.12	$168.65 - $218.88
Q2 2023	8,057	$1,530	$198.26	$183.00 - $212.47
Q1 2023	8,814	$1,766	$210.20	$179.19 - $242.39
Q4 2022	12,041	$2,862	$213.29	$181.65 - $242.97
Q3 2022	12,008	$2,404	$190.74	$135.46 - $236.80
Q2 2022	11,389	$1,661	$141.87	$117.58 - $180.35
Q1 2022	15,190	$2,481	$152.35	$125.00 - $174.66
Q4 2021	19,846	$3,365	$185.86	$154.82 - $212.00
Q3 2021	28,207	$5,326	$187.58	$166.16 - $209.73
Q2 2021	25,369	$4,301	$146.46	$125.08 - $177.53
Q1 2021	18,386	$2,596	$150.49	$124.00 - $178.41
Q4 2020	20,017	$2,602	$133.53	$119.29 - $148.76
Q3 2020	20,694	$3,013	$142.10	$119.67 - $167.33
Q2 2020	20,172	$2,988	$134.81	$98.01 - $158.37
Q1 2020	17,389	$1,893	$115.43	$84.97 - $134.51
Q4 2019	26,775	$3,084	$99.70	$73.32 - $125.72
Q3 2019	32,719	$2,631	$79.11	$69.11 - $88.00
Q2 2019	33,396	$2,423	$76.72	$65.81 - $96.08
Q1 2019	39,919	$3,730	$83.64	$70.29 - $93.95
Q4 2018	36,887	$2,689	$76.92	$60.27 - $90.00
Q3 2018	44,214	$3,870	$100.59	$86.95 - $124.22
Q2 2018	44,233	$4,357	$99.19	$87.35 - $118.71
Q1 2018	48,265	$5,748	$128.92	$108.13 - $153.99
Q4 2017	55,630	$7,068	$125.65	$111.25 - $147.63
Q3 2017	53,478	$6,283	$85.36	$70.76 - $119.02
Q2 2017	48,505	$3,869	$63.91	$46.90 - $86.92
Q1 2017	47,427	$2,431	$46.22	$35.98 - $60.41
Q4 2016	57,713	$2,161	$41.87	$31.38 - $71.67
Q3 2016	56,206	$3,810	$70.55	$53.56 - $80.11
Q2 2016	66,151	$3,671	$63.00	$49.96 - $75.08
Q1 2016	64,623	$4,056	$66.49	$51.51 - $98.00
Q4 2015	70,904	$6,675	$92.72	$71.14 - $110.75
Q3 2015	67,222	$5,402	$111.10	$76.46 - $137.89
Q2 2015	71,340	$8,552	$119.50	$98.63 - $140.00
Q1 2015	71,269	$7,442	$101.34	$82.06 - $121.93
Q4 2014	54,541	$5,290	$92.65	$72.80 - $111.49
Q3 2014	41,789	$3,264	$64.51	$51.93 - $79.88
Q2 2014	48,693	$3,076	$59.44	$47.03 - $71.40
Q1 2014	109,698	$7,365	$77.42	$60.24 - $112.57
Q4 2013	33,864	$2,178	$59.65	$48.16 - $67.97
Q3 2013	60,223	$3,855	$49.85	$31.75 - $65.83
Q2 2013	47,671	$1,478	$26.61	$21.60 - $31.79