ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Bank of New York Mellon Corp's Holding History (CIK: 0001390777)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 504,133 Value ($000) $200,469 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 419,783 Value ($000) $191,421 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 429,769 Value ($000) $140,143 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 474,832 Value ($000) $128,214 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 479,203 Value ($000) $112,761 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 474,439 Value ($000) $130,485 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 673,702 Value ($000) $163,709 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 798,445 Value ($000) $119,327 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 837,131 Value ($000) $160,235 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 837,084 Value ($000) $148,247 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 775,596 Value ($000) $147,317 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 554,337 Value ($000) $111,045 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 574,385 Value ($000) $136,502 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 567,138 Value ($000) $113,517 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 675,155 Value ($000) $98,471 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 638,868 Value ($000) $104,321 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 602,314 Value ($000) $102,141 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 453,250 Value ($000) $85,578 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 442,001 Value ($000) $74,928 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 421,814 Value ($000) $59,556 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 442,688 Value ($000) $57,536 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 434,955 Value ($000) $63,330 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 434,775 Value ($000) $64,395 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 443,264 Value ($000) $48,248 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 442,143 Value ($000) $50,923 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 450,703 Value ($000) $36,245 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 400,693 Value ($000) $29,075 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 390,198 Value ($000) $36,463 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 495,993 Value ($000) $36,163 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 512,170 Value ($000) $44,825 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 511,961 Value ($000) $50,423 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 398,311 Value ($000) $47,438 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 395,267 Value ($000) $50,219 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 342,105 Value ($000) $40,194 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 333,942 Value ($000) $26,634 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 305,682 Value ($000) $15,666 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 302,783 Value ($000) $11,336 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 326,562 Value ($000) $22,134 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 348,636 Value ($000) $19,345 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 317,676 Value ($000) $19,941 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 312,051 Value ($000) $29,376 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 319,274 Value ($000) $25,657 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 312,809 Value ($000) $37,497 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 298,785 Value ($000) $31,198 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 266,319 Value ($000) $25,834 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 269,225 Value ($000) $21,027 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 266,888 Value ($000) $16,859 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 335,950 Value ($000) $22,556 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 335,204 Value ($000) $21,554 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 515,324 Value ($000) $32,985 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 567,590 Value ($000) $17,595 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	504,133	$200,469	$442.56	$387.03 - $495.55
Q3 2025	419,783	$191,421	$407.20	$309.57 - $484.21
Q2 2025	429,769	$140,143	$276.71	$205.87 - $327.21
Q1 2025	474,832	$128,214	$257.00	$230.79 - $300.90
Q4 2024	479,203	$112,761	$262.99	$229.86 - $304.39
Q3 2024	474,439	$130,485	$260.36	$231.01 - $287.55
Q2 2024	673,702	$163,709	$157.87	$141.98 - $252.87
Q1 2024	798,445	$119,327	$166.82	$143.52 - $199.38
Q4 2023	837,131	$160,235	$170.34	$148.10 - $198.00
Q3 2023	837,084	$148,247	$191.12	$168.65 - $218.88
Q2 2023	775,596	$147,317	$198.26	$183.00 - $212.47
Q1 2023	554,337	$111,045	$210.20	$179.19 - $242.39
Q4 2022	574,385	$136,502	$213.29	$181.65 - $242.97
Q3 2022	567,138	$113,517	$190.74	$135.46 - $236.80
Q2 2022	675,155	$98,471	$141.87	$117.58 - $180.35
Q1 2022	638,868	$104,321	$152.35	$125.00 - $174.66
Q4 2021	602,314	$102,141	$185.86	$154.82 - $212.00
Q3 2021	453,250	$85,578	$187.58	$166.16 - $209.73
Q2 2021	442,001	$74,928	$146.46	$125.08 - $177.53
Q1 2021	421,814	$59,556	$150.49	$124.00 - $178.41
Q4 2020	442,688	$57,536	$133.53	$119.29 - $148.76
Q3 2020	434,955	$63,330	$142.10	$119.67 - $167.33
Q2 2020	434,775	$64,395	$134.81	$98.01 - $158.37
Q1 2020	443,264	$48,248	$115.43	$84.97 - $134.51
Q4 2019	442,143	$50,923	$99.70	$73.32 - $125.72
Q3 2019	450,703	$36,245	$79.11	$69.11 - $88.00
Q2 2019	400,693	$29,075	$76.72	$65.81 - $96.08
Q1 2019	390,198	$36,463	$83.64	$70.29 - $93.95
Q4 2018	495,993	$36,163	$76.92	$60.27 - $90.00
Q3 2018	512,170	$44,825	$100.59	$86.95 - $124.22
Q2 2018	511,961	$50,423	$99.19	$87.35 - $118.71
Q1 2018	398,311	$47,438	$128.92	$108.13 - $153.99
Q4 2017	395,267	$50,219	$125.65	$111.25 - $147.63
Q3 2017	342,105	$40,194	$85.36	$70.76 - $119.02
Q2 2017	333,942	$26,634	$63.91	$46.90 - $86.92
Q1 2017	305,682	$15,666	$46.22	$35.98 - $60.41
Q4 2016	302,783	$11,336	$41.87	$31.38 - $71.67
Q3 2016	326,562	$22,134	$70.55	$53.56 - $80.11
Q2 2016	348,636	$19,345	$63.00	$49.96 - $75.08
Q1 2016	317,676	$19,941	$66.49	$51.51 - $98.00
Q4 2015	312,051	$29,376	$92.72	$71.14 - $110.75
Q3 2015	319,274	$25,657	$111.10	$76.46 - $137.89
Q2 2015	312,809	$37,497	$119.50	$98.63 - $140.00
Q1 2015	298,785	$31,198	$101.34	$82.06 - $121.93
Q4 2014	266,319	$25,834	$92.65	$72.80 - $111.49
Q3 2014	269,225	$21,027	$64.51	$51.93 - $79.88
Q2 2014	266,888	$16,859	$59.44	$47.03 - $71.40
Q1 2014	335,950	$22,556	$77.42	$60.24 - $112.57
Q4 2013	335,204	$21,554	$59.65	$48.16 - $67.97
Q3 2013	515,324	$32,985	$49.85	$31.75 - $65.83
Q2 2013	567,590	$17,595	$26.61	$21.60 - $31.79