ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 38,459 Value ($000) $15,293 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 221,843 Value ($000) $101,160 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 601,199 Value ($000) $196,045 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 4,236 Value ($000) $1,144 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 65,393 Value ($000) $15,388 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 23,932 Value ($000) $6,582 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 367,289 Value ($000) $89,251 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 39,984 Value ($000) $5,976 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 66,649 Value ($000) $12,757 Avg Close $170.34 Range $148.10 - $198.00

Q2 2023

Shares 29,563 Value ($000) $5,615 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 104,336 Value ($000) $20,901 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 1,440 Value ($000) $342 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 82,572 Value ($000) $16,527 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 7,694 Value ($000) $1,123 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 2,108 Value ($000) $344 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 70,768 Value ($000) $12,001 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 20,879 Value ($000) $3,942 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 38,949 Value ($000) $6,603 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 123,226 Value ($000) $17,398 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 80,961 Value ($000) $10,522 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 26,533 Value ($000) $3,863 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 73,700 Value ($000) $10,916 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 110,358 Value ($000) $12,013 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 80,773 Value ($000) $9,303 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 80,406 Value ($000) $6,466 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 966,044 Value ($000) $70,096 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 12,304 Value ($000) $1,150 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 29,620 Value ($000) $2,160 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 35,476 Value ($000) $3,105 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 36,688 Value ($000) $3,613 Avg Close $99.19 Range $87.35 - $118.71

Q4 2017

Shares 57,507 Value ($000) $7,307 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 45,221 Value ($000) $5,313 Avg Close $85.36 Range $70.76 - $119.02

Q4 2016

Shares 9,632 Value ($000) $361 Avg Close $41.87 Range $31.38 - $71.67

Q1 2016

Shares 730,736 Value ($000) $45,868 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 181,538 Value ($000) $17,090 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 139,428 Value ($000) $11,204 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 4,019 Value ($000) $482 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 4,130 Value ($000) $431 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 9,540 Value ($000) $925 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 251,350 Value ($000) $19,631 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 1,981 Value ($000) $125 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 26,519 Value ($000) $1,781 Avg Close $77.42 Range $60.24 - $112.57

Q3 2013

Shares 273,219 Value ($000) $17,489 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 1,187,896 Value ($000) $36,836 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	38,459	$15,293	$442.56	$387.03 - $495.55
Q3 2025	221,843	$101,160	$407.20	$309.57 - $484.21
Q2 2025	601,199	$196,045	$276.71	$205.87 - $327.21
Q1 2025	4,236	$1,144	$257.00	$230.79 - $300.90
Q4 2024	65,393	$15,388	$262.99	$229.86 - $304.39
Q3 2024	23,932	$6,582	$260.36	$231.01 - $287.55
Q2 2024	367,289	$89,251	$157.87	$141.98 - $252.87
Q1 2024	39,984	$5,976	$166.82	$143.52 - $199.38
Q4 2023	66,649	$12,757	$170.34	$148.10 - $198.00
Q2 2023	29,563	$5,615	$198.26	$183.00 - $212.47
Q1 2023	104,336	$20,901	$210.20	$179.19 - $242.39
Q4 2022	1,440	$342	$213.29	$181.65 - $242.97
Q3 2022	82,572	$16,527	$190.74	$135.46 - $236.80
Q2 2022	7,694	$1,123	$141.87	$117.58 - $180.35
Q1 2022	2,108	$344	$152.35	$125.00 - $174.66
Q4 2021	70,768	$12,001	$185.86	$154.82 - $212.00
Q3 2021	20,879	$3,942	$187.58	$166.16 - $209.73
Q2 2021	38,949	$6,603	$146.46	$125.08 - $177.53
Q1 2021	123,226	$17,398	$150.49	$124.00 - $178.41
Q4 2020	80,961	$10,522	$133.53	$119.29 - $148.76
Q3 2020	26,533	$3,863	$142.10	$119.67 - $167.33
Q2 2020	73,700	$10,916	$134.81	$98.01 - $158.37
Q1 2020	110,358	$12,013	$115.43	$84.97 - $134.51
Q4 2019	80,773	$9,303	$99.70	$73.32 - $125.72
Q3 2019	80,406	$6,466	$79.11	$69.11 - $88.00
Q2 2019	966,044	$70,096	$76.72	$65.81 - $96.08
Q1 2019	12,304	$1,150	$83.64	$70.29 - $93.95
Q4 2018	29,620	$2,160	$76.92	$60.27 - $90.00
Q3 2018	35,476	$3,105	$100.59	$86.95 - $124.22
Q2 2018	36,688	$3,613	$99.19	$87.35 - $118.71
Q4 2017	57,507	$7,307	$125.65	$111.25 - $147.63
Q3 2017	45,221	$5,313	$85.36	$70.76 - $119.02
Q4 2016	9,632	$361	$41.87	$31.38 - $71.67
Q1 2016	730,736	$45,868	$66.49	$51.51 - $98.00
Q4 2015	181,538	$17,090	$92.72	$71.14 - $110.75
Q3 2015	139,428	$11,204	$111.10	$76.46 - $137.89
Q2 2015	4,019	$482	$119.50	$98.63 - $140.00
Q1 2015	4,130	$431	$101.34	$82.06 - $121.93
Q4 2014	9,540	$925	$92.65	$72.80 - $111.49
Q3 2014	251,350	$19,631	$64.51	$51.93 - $79.88
Q2 2014	1,981	$125	$59.44	$47.03 - $71.40
Q1 2014	26,519	$1,781	$77.42	$60.24 - $112.57
Q3 2013	273,219	$17,489	$49.85	$31.75 - $65.83
Q2 2013	1,187,896	$36,836	$26.61	$21.60 - $31.79