ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Quantitative Investment Management, LLC's Holding History (CIK: 0001445911)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 4,331 Value ($000) $2 Avg Close $442.56 Range $387.03 - $495.55

Q2 2025

Shares 1,238 Value ($000) $0 Avg Close $276.71 Range $205.87 - $327.21

Q4 2024

Shares 11,010 Value ($000) $3 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 802 Value ($000) $0 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 9,336 Value ($000) $2 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 3,469 Value ($000) $1 Avg Close $166.82 Range $143.52 - $199.38

Q3 2021

Shares 14,293 Value ($000) $2,698 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 23,325 Value ($000) $3,954 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 15,851 Value ($000) $2,238 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 5,872 Value ($000) $763 Avg Close $133.53 Range $119.29 - $148.76

Q2 2020

Shares 40,945 Value ($000) $6,064 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 20,738 Value ($000) $2,257 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 130,792 Value ($000) $15,063 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 68,008 Value ($000) $5,469 Avg Close $79.11 Range $69.11 - $88.00

Q1 2019

Shares 12,000 Value ($000) $1,121 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 19,900 Value ($000) $1,450 Avg Close $76.92 Range $60.27 - $90.00

Q1 2018

Shares 57,800 Value ($000) $6,883 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 3,900 Value ($000) $495 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 4,900 Value ($000) $575 Avg Close $85.36 Range $70.76 - $119.02

Q4 2016

Shares 98,400 Value ($000) $3,684 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 8,600 Value ($000) $582 Avg Close $70.55 Range $53.56 - $80.11

Q4 2015

Shares 9,300 Value ($000) $875 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 16,300 Value ($000) $1,309 Avg Close $111.10 Range $76.46 - $137.89

Q4 2014

Shares 3,300 Value ($000) $320 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 3,800 Value ($000) $296 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 10,900 Value ($000) $688 Avg Close $59.44 Range $47.03 - $71.40

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	4,331	$2	$442.56	$387.03 - $495.55
Q2 2025	1,238	$0	$276.71	$205.87 - $327.21
Q4 2024	11,010	$3	$262.99	$229.86 - $304.39
Q3 2024	802	$0	$260.36	$231.01 - $287.55
Q2 2024	9,336	$2	$157.87	$141.98 - $252.87
Q1 2024	3,469	$1	$166.82	$143.52 - $199.38
Q3 2021	14,293	$2,698	$187.58	$166.16 - $209.73
Q2 2021	23,325	$3,954	$146.46	$125.08 - $177.53
Q1 2021	15,851	$2,238	$150.49	$124.00 - $178.41
Q4 2020	5,872	$763	$133.53	$119.29 - $148.76
Q2 2020	40,945	$6,064	$134.81	$98.01 - $158.37
Q1 2020	20,738	$2,257	$115.43	$84.97 - $134.51
Q4 2019	130,792	$15,063	$99.70	$73.32 - $125.72
Q3 2019	68,008	$5,469	$79.11	$69.11 - $88.00
Q1 2019	12,000	$1,121	$83.64	$70.29 - $93.95
Q4 2018	19,900	$1,450	$76.92	$60.27 - $90.00
Q1 2018	57,800	$6,883	$128.92	$108.13 - $153.99
Q4 2017	3,900	$495	$125.65	$111.25 - $147.63
Q3 2017	4,900	$575	$85.36	$70.76 - $119.02
Q4 2016	98,400	$3,684	$41.87	$31.38 - $71.67
Q3 2016	8,600	$582	$70.55	$53.56 - $80.11
Q4 2015	9,300	$875	$92.72	$71.14 - $110.75
Q3 2015	16,300	$1,309	$111.10	$76.46 - $137.89
Q4 2014	3,300	$320	$92.65	$72.80 - $111.49
Q3 2014	3,800	$296	$64.51	$51.93 - $79.88
Q2 2014	10,900	$688	$59.44	$47.03 - $71.40