ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 6,704 Value ($000) $2 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 4,829 Value ($000) $1 Avg Close $262.99 Range $229.86 - $304.39

Q2 2024

Shares 8,803 Value ($000) $2 Avg Close $157.87 Range $141.98 - $252.87

Q4 2023

Shares 2,916 Value ($000) $1 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 6,845 Value ($000) $1 Avg Close $191.12 Range $168.65 - $218.88

Q1 2023

Shares 13,723 Value ($000) $3 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 8,877 Value ($000) $2 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 9 Value ($000) $1 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 1,077 Value ($000) $157 Avg Close $141.87 Range $117.58 - $180.35

Q3 2021

Shares 15,991 Value ($000) $2,714 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 15,284 Value ($000) $2,590 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 14,386 Value ($000) $2,031 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 8,075 Value ($000) $1,049 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 269 Value ($000) $39 Avg Close $142.10 Range $119.67 - $167.33

Q1 2020

Shares 14,470 Value ($000) $1,575 Avg Close $115.43 Range $84.97 - $134.51

Q1 2019

Shares 2,772 Value ($000) $259 Avg Close $83.64 Range $70.29 - $93.95

Q4 2017

Shares 5,971 Value ($000) $758 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 12,394 Value ($000) $1,456 Avg Close $85.36 Range $70.76 - $119.02

Q1 2017

Shares 32,718 Value ($000) $1,676 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 7,731 Value ($000) $289 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 8,756 Value ($000) $593 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 14,750 Value ($000) $818 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 7,102 Value ($000) $445 Avg Close $66.49 Range $51.51 - $98.00

Q3 2015

Shares 4,335 Value ($000) $348 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 7,883 Value ($000) $944 Avg Close $119.50 Range $98.63 - $140.00

Q4 2014

Shares 853 Value ($000) $83 Avg Close $92.65 Range $72.80 - $111.49

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	6,704	$2	$257.00	$230.79 - $300.90
Q4 2024	4,829	$1	$262.99	$229.86 - $304.39
Q2 2024	8,803	$2	$157.87	$141.98 - $252.87
Q4 2023	2,916	$1	$170.34	$148.10 - $198.00
Q3 2023	6,845	$1	$191.12	$168.65 - $218.88
Q1 2023	13,723	$3	$210.20	$179.19 - $242.39
Q4 2022	8,877	$2	$213.29	$181.65 - $242.97
Q3 2022	9	$1	$190.74	$135.46 - $236.80
Q2 2022	1,077	$157	$141.87	$117.58 - $180.35
Q3 2021	15,991	$2,714	$187.58	$166.16 - $209.73
Q2 2021	15,284	$2,590	$146.46	$125.08 - $177.53
Q1 2021	14,386	$2,031	$150.49	$124.00 - $178.41
Q4 2020	8,075	$1,049	$133.53	$119.29 - $148.76
Q3 2020	269	$39	$142.10	$119.67 - $167.33
Q1 2020	14,470	$1,575	$115.43	$84.97 - $134.51
Q1 2019	2,772	$259	$83.64	$70.29 - $93.95
Q4 2017	5,971	$758	$125.65	$111.25 - $147.63
Q3 2017	12,394	$1,456	$85.36	$70.76 - $119.02
Q1 2017	32,718	$1,676	$46.22	$35.98 - $60.41
Q4 2016	7,731	$289	$41.87	$31.38 - $71.67
Q3 2016	8,756	$593	$70.55	$53.56 - $80.11
Q2 2016	14,750	$818	$63.00	$49.96 - $75.08
Q1 2016	7,102	$445	$66.49	$51.51 - $98.00
Q3 2015	4,335	$348	$111.10	$76.46 - $137.89
Q2 2015	7,883	$944	$119.50	$98.63 - $140.00
Q4 2014	853	$83	$92.65	$72.80 - $111.49