ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 359,200 Value ($000) $142,836 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 375,800 Value ($000) $171,365 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 393,800 Value ($000) $128,414 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 364,200 Value ($000) $98,341 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 362,600 Value ($000) $85,323 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 375,400 Value ($000) $103,246 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 374,400 Value ($000) $90,979 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 375,900 Value ($000) $56,178 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 390,800 Value ($000) $74,803 Avg Close $170.34 Range $148.10 - $198.00

Q3 2023

Shares 400,600 Value ($000) $70,946 Avg Close $191.12 Range $168.65 - $218.88

Q2 2023

Shares 447,600 Value ($000) $85,017 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 488,300 Value ($000) $97,816 Avg Close $210.20 Range $179.19 - $242.39

Q4 2022

Shares 488,100 Value ($000) $115,997 Avg Close $213.29 Range $181.65 - $242.97

Q3 2022

Shares 523,610 Value ($000) $104,806 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 521,410 Value ($000) $76,048 Avg Close $141.87 Range $117.58 - $180.35

Q1 2022

Shares 518,010 Value ($000) $84,586 Avg Close $152.35 Range $125.00 - $174.66

Q4 2021

Shares 451,710 Value ($000) $76,601 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 464,610 Value ($000) $87,723 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 476,910 Value ($000) $80,846 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 446,824 Value ($000) $63,087 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 438,024 Value ($000) $56,930 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 446,924 Value ($000) $65,072 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 445,424 Value ($000) $65,972 Avg Close $134.81 Range $98.01 - $158.37

Q1 2020

Shares 432,624 Value ($000) $47,091 Avg Close $115.43 Range $84.97 - $134.51

Q4 2019

Shares 350,624 Value ($000) $40,381 Avg Close $99.70 Range $73.32 - $125.72

Q3 2019

Shares 365,424 Value ($000) $29,387 Avg Close $79.11 Range $69.11 - $88.00

Q2 2019

Shares 311,900 Value ($000) $22,631 Avg Close $76.72 Range $65.81 - $96.08

Q1 2019

Shares 302,800 Value ($000) $28,297 Avg Close $83.64 Range $70.29 - $93.95

Q4 2018

Shares 294,300 Value ($000) $21,457 Avg Close $76.92 Range $60.27 - $90.00

Q3 2018

Shares 288,900 Value ($000) $25,285 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 296,600 Value ($000) $29,212 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 282,900 Value ($000) $33,693 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 326,500 Value ($000) $41,482 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 137,900 Value ($000) $16,202 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 137,900 Value ($000) $10,999 Avg Close $63.91 Range $46.90 - $86.92

Q1 2017

Shares 127,700 Value ($000) $6,545 Avg Close $46.22 Range $35.98 - $60.41

Q4 2016

Shares 126,900 Value ($000) $4,751 Avg Close $41.87 Range $31.38 - $71.67

Q3 2016

Shares 212,800 Value ($000) $14,424 Avg Close $70.55 Range $53.56 - $80.11

Q2 2016

Shares 214,900 Value ($000) $11,925 Avg Close $63.00 Range $49.96 - $75.08

Q1 2016

Shares 198,200 Value ($000) $11,923 Avg Close $66.49 Range $51.51 - $98.00

Q4 2015

Shares 138,300 Value ($000) $13,020 Avg Close $92.72 Range $71.14 - $110.75

Q3 2015

Shares 134,900 Value ($000) $10,841 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 121,900 Value ($000) $14,612 Avg Close $119.50 Range $98.63 - $140.00

Q1 2015

Shares 82,800 Value ($000) $8,646 Avg Close $101.34 Range $82.06 - $121.93

Q4 2014

Shares 71,600 Value ($000) $6,945 Avg Close $92.65 Range $72.80 - $111.49

Q3 2014

Shares 67,900 Value ($000) $5,303 Avg Close $64.51 Range $51.93 - $79.88

Q2 2014

Shares 60,800 Value ($000) $3,841 Avg Close $59.44 Range $47.03 - $71.40

Q1 2014

Shares 63,500 Value ($000) $4,263 Avg Close $77.42 Range $60.24 - $112.57

Q4 2013

Shares 49,100 Value ($000) $3,159 Avg Close $59.65 Range $48.16 - $67.97

Q3 2013

Shares 48,600 Value ($000) $3,111 Avg Close $49.85 Range $31.75 - $65.83

Q2 2013

Shares 50,800 Value ($000) $1,575 Avg Close $26.61 Range $21.60 - $31.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	359,200	$142,836	$442.56	$387.03 - $495.55
Q3 2025	375,800	$171,365	$407.20	$309.57 - $484.21
Q2 2025	393,800	$128,414	$276.71	$205.87 - $327.21
Q1 2025	364,200	$98,341	$257.00	$230.79 - $300.90
Q4 2024	362,600	$85,323	$262.99	$229.86 - $304.39
Q3 2024	375,400	$103,246	$260.36	$231.01 - $287.55
Q2 2024	374,400	$90,979	$157.87	$141.98 - $252.87
Q1 2024	375,900	$56,178	$166.82	$143.52 - $199.38
Q4 2023	390,800	$74,803	$170.34	$148.10 - $198.00
Q3 2023	400,600	$70,946	$191.12	$168.65 - $218.88
Q2 2023	447,600	$85,017	$198.26	$183.00 - $212.47
Q1 2023	488,300	$97,816	$210.20	$179.19 - $242.39
Q4 2022	488,100	$115,997	$213.29	$181.65 - $242.97
Q3 2022	523,610	$104,806	$190.74	$135.46 - $236.80
Q2 2022	521,410	$76,048	$141.87	$117.58 - $180.35
Q1 2022	518,010	$84,586	$152.35	$125.00 - $174.66
Q4 2021	451,710	$76,601	$185.86	$154.82 - $212.00
Q3 2021	464,610	$87,723	$187.58	$166.16 - $209.73
Q2 2021	476,910	$80,846	$146.46	$125.08 - $177.53
Q1 2021	446,824	$63,087	$150.49	$124.00 - $178.41
Q4 2020	438,024	$56,930	$133.53	$119.29 - $148.76
Q3 2020	446,924	$65,072	$142.10	$119.67 - $167.33
Q2 2020	445,424	$65,972	$134.81	$98.01 - $158.37
Q1 2020	432,624	$47,091	$115.43	$84.97 - $134.51
Q4 2019	350,624	$40,381	$99.70	$73.32 - $125.72
Q3 2019	365,424	$29,387	$79.11	$69.11 - $88.00
Q2 2019	311,900	$22,631	$76.72	$65.81 - $96.08
Q1 2019	302,800	$28,297	$83.64	$70.29 - $93.95
Q4 2018	294,300	$21,457	$76.92	$60.27 - $90.00
Q3 2018	288,900	$25,285	$100.59	$86.95 - $124.22
Q2 2018	296,600	$29,212	$99.19	$87.35 - $118.71
Q1 2018	282,900	$33,693	$128.92	$108.13 - $153.99
Q4 2017	326,500	$41,482	$125.65	$111.25 - $147.63
Q3 2017	137,900	$16,202	$85.36	$70.76 - $119.02
Q2 2017	137,900	$10,999	$63.91	$46.90 - $86.92
Q1 2017	127,700	$6,545	$46.22	$35.98 - $60.41
Q4 2016	126,900	$4,751	$41.87	$31.38 - $71.67
Q3 2016	212,800	$14,424	$70.55	$53.56 - $80.11
Q2 2016	214,900	$11,925	$63.00	$49.96 - $75.08
Q1 2016	198,200	$11,923	$66.49	$51.51 - $98.00
Q4 2015	138,300	$13,020	$92.72	$71.14 - $110.75
Q3 2015	134,900	$10,841	$111.10	$76.46 - $137.89
Q2 2015	121,900	$14,612	$119.50	$98.63 - $140.00
Q1 2015	82,800	$8,646	$101.34	$82.06 - $121.93
Q4 2014	71,600	$6,945	$92.65	$72.80 - $111.49
Q3 2014	67,900	$5,303	$64.51	$51.93 - $79.88
Q2 2014	60,800	$3,841	$59.44	$47.03 - $71.40
Q1 2014	63,500	$4,263	$77.42	$60.24 - $112.57
Q4 2013	49,100	$3,159	$59.65	$48.16 - $67.97
Q3 2013	48,600	$3,111	$49.85	$31.75 - $65.83
Q2 2013	50,800	$1,575	$26.61	$21.60 - $31.79