ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 6,197 Value ($000) $2,826 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 201,396 Value ($000) $65,673 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 300,635 Value ($000) $81,178 Avg Close $257.00 Range $230.79 - $300.90

Q1 2024

Shares 206,255 Value ($000) $30,825 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 85,990 Value ($000) $16,459 Avg Close $170.34 Range $148.10 - $198.00

Q3 2022

Shares 14,570 Value ($000) $2,916 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 333,200 Value ($000) $48,597 Avg Close $141.87 Range $117.58 - $180.35

Q3 2021

Shares 99,512 Value ($000) $18,789 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 119,689 Value ($000) $20,290 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 439,937 Value ($000) $62,115 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 481,900 Value ($000) $62,633 Avg Close $133.53 Range $119.29 - $148.76

Q2 2019

Shares 398,928 Value ($000) $28,946 Avg Close $76.72 Range $65.81 - $96.08

Q3 2018

Shares 885,312 Value ($000) $77,483 Avg Close $100.59 Range $86.95 - $124.22

Q2 2018

Shares 1,356,408 Value ($000) $133,593 Avg Close $99.19 Range $87.35 - $118.71

Q1 2018

Shares 908,046 Value ($000) $108,148 Avg Close $128.92 Range $108.13 - $153.99

Q4 2017

Shares 88,886 Value ($000) $11,293 Avg Close $125.65 Range $111.25 - $147.63

Q3 2017

Shares 85,000 Value ($000) $9,987 Avg Close $85.36 Range $70.76 - $119.02

Q2 2017

Shares 50,000 Value ($000) $3,988 Avg Close $63.91 Range $46.90 - $86.92

Q3 2014

Shares 12,100 Value ($000) $945 Avg Close $64.51 Range $51.93 - $79.88

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	6,197	$2,826	$407.20	$309.57 - $484.21
Q2 2025	201,396	$65,673	$276.71	$205.87 - $327.21
Q1 2025	300,635	$81,178	$257.00	$230.79 - $300.90
Q1 2024	206,255	$30,825	$166.82	$143.52 - $199.38
Q4 2023	85,990	$16,459	$170.34	$148.10 - $198.00
Q3 2022	14,570	$2,916	$190.74	$135.46 - $236.80
Q2 2022	333,200	$48,597	$141.87	$117.58 - $180.35
Q3 2021	99,512	$18,789	$187.58	$166.16 - $209.73
Q2 2021	119,689	$20,290	$146.46	$125.08 - $177.53
Q1 2021	439,937	$62,115	$150.49	$124.00 - $178.41
Q4 2020	481,900	$62,633	$133.53	$119.29 - $148.76
Q2 2019	398,928	$28,946	$76.72	$65.81 - $96.08
Q3 2018	885,312	$77,483	$100.59	$86.95 - $124.22
Q2 2018	1,356,408	$133,593	$99.19	$87.35 - $118.71
Q1 2018	908,046	$108,148	$128.92	$108.13 - $153.99
Q4 2017	88,886	$11,293	$125.65	$111.25 - $147.63
Q3 2017	85,000	$9,987	$85.36	$70.76 - $119.02
Q2 2017	50,000	$3,988	$63.91	$46.90 - $86.92
Q3 2014	12,100	$945	$64.51	$51.93 - $79.88