ALNYLAM PHARMACEUTICALS INC

Ticker: ALNY CUSIP: 02043Q107 Class: EQTY

Engineers Gate Manager LP's Holding History (CIK: 0001620220)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 20,199 Value ($000) $8,032 Avg Close $442.56 Range $387.03 - $495.55

Q3 2025

Shares 43,849 Value ($000) $19,995 Avg Close $407.20 Range $309.57 - $484.21

Q2 2025

Shares 32,630 Value ($000) $10,640 Avg Close $276.71 Range $205.87 - $327.21

Q1 2025

Shares 25,392 Value ($000) $6,856 Avg Close $257.00 Range $230.79 - $300.90

Q4 2024

Shares 33,897 Value ($000) $7,976 Avg Close $262.99 Range $229.86 - $304.39

Q3 2024

Shares 11,863 Value ($000) $3,263 Avg Close $260.36 Range $231.01 - $287.55

Q2 2024

Shares 7,074 Value ($000) $1,719 Avg Close $157.87 Range $141.98 - $252.87

Q1 2024

Shares 24,723 Value ($000) $3,695 Avg Close $166.82 Range $143.52 - $199.38

Q4 2023

Shares 17,431 Value ($000) $3,336 Avg Close $170.34 Range $148.10 - $198.00

Q2 2023

Shares 5,286 Value ($000) $1,004 Avg Close $198.26 Range $183.00 - $212.47

Q1 2023

Shares 6,195 Value ($000) $1,241 Avg Close $210.20 Range $179.19 - $242.39

Q3 2022

Shares 1,957 Value ($000) $392 Avg Close $190.74 Range $135.46 - $236.80

Q2 2022

Shares 5,424 Value ($000) $791 Avg Close $141.87 Range $117.58 - $180.35

Q4 2021

Shares 1,990 Value ($000) $337 Avg Close $185.86 Range $154.82 - $212.00

Q3 2021

Shares 1,134 Value ($000) $214 Avg Close $187.58 Range $166.16 - $209.73

Q2 2021

Shares 15,964 Value ($000) $2,706 Avg Close $146.46 Range $125.08 - $177.53

Q1 2021

Shares 2,910 Value ($000) $411 Avg Close $150.49 Range $124.00 - $178.41

Q4 2020

Shares 2,490 Value ($000) $324 Avg Close $133.53 Range $119.29 - $148.76

Q3 2020

Shares 1,400 Value ($000) $204 Avg Close $142.10 Range $119.67 - $167.33

Q2 2020

Shares 3,500 Value ($000) $518 Avg Close $134.81 Range $98.01 - $158.37

Q4 2019

Shares 3,260 Value ($000) $375 Avg Close $99.70 Range $73.32 - $125.72

Q3 2015

Shares 4,600 Value ($000) $370 Avg Close $111.10 Range $76.46 - $137.89

Q2 2015

Shares 2,500 Value ($000) $300 Avg Close $119.50 Range $98.63 - $140.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	20,199	$8,032	$442.56	$387.03 - $495.55
Q3 2025	43,849	$19,995	$407.20	$309.57 - $484.21
Q2 2025	32,630	$10,640	$276.71	$205.87 - $327.21
Q1 2025	25,392	$6,856	$257.00	$230.79 - $300.90
Q4 2024	33,897	$7,976	$262.99	$229.86 - $304.39
Q3 2024	11,863	$3,263	$260.36	$231.01 - $287.55
Q2 2024	7,074	$1,719	$157.87	$141.98 - $252.87
Q1 2024	24,723	$3,695	$166.82	$143.52 - $199.38
Q4 2023	17,431	$3,336	$170.34	$148.10 - $198.00
Q2 2023	5,286	$1,004	$198.26	$183.00 - $212.47
Q1 2023	6,195	$1,241	$210.20	$179.19 - $242.39
Q3 2022	1,957	$392	$190.74	$135.46 - $236.80
Q2 2022	5,424	$791	$141.87	$117.58 - $180.35
Q4 2021	1,990	$337	$185.86	$154.82 - $212.00
Q3 2021	1,134	$214	$187.58	$166.16 - $209.73
Q2 2021	15,964	$2,706	$146.46	$125.08 - $177.53
Q1 2021	2,910	$411	$150.49	$124.00 - $178.41
Q4 2020	2,490	$324	$133.53	$119.29 - $148.76
Q3 2020	1,400	$204	$142.10	$119.67 - $167.33
Q2 2020	3,500	$518	$134.81	$98.01 - $158.37
Q4 2019	3,260	$375	$99.70	$73.32 - $125.72
Q3 2015	4,600	$370	$111.10	$76.46 - $137.89
Q2 2015	2,500	$300	$119.50	$98.63 - $140.00