ALPINE IMMUNE SCIENCES INC

CUSIP: 02083G100 Class: Common Stock

DEERFIELD MANAGEMENT COMPANY, L.P.'s Holding History (CIK: 0001009258)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 248,992 Value ($000) $956 Avg Close — Range —
Q3 2019
Shares 406,926 Value ($000) $1,611 Avg Close — Range —
Q2 2019
Shares 415,908 Value ($000) $1,751 Avg Close — Range —
Q1 2019
Shares 475,450 Value ($000) $3,262 Avg Close — Range —
Q4 2018
Shares 475,450 Value ($000) $1,750 Avg Close — Range —
Q3 2018
Shares 612,867 Value ($000) $3,879 Avg Close — Range —
Q2 2018
Shares 913,100 Value ($000) $6,912 Avg Close — Range —
Q1 2018
Shares 913,100 Value ($000) $7,305 Avg Close — Range —
Q4 2017
Shares 913,100 Value ($000) $10,227 Avg Close — Range —
Q3 2017
Shares 933,100 Value ($000) $10,824 Avg Close — Range —