ALPINE IMMUNE SCIENCES INC

CUSIP: 02083G100 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2024
Shares 668,775 Value ($000) $26,510 Avg Close — Range —
Q4 2023
Shares 264,075 Value ($000) $5,033 Avg Close — Range —
Q3 2023
Shares 246,075 Value ($000) $2,818 Avg Close — Range —
Q2 2023
Shares 86,375 Value ($000) $888 Avg Close — Range —
Q1 2023
Shares 40,975 Value ($000) $316 Avg Close — Range —
Q4 2022
Shares 65,175 Value ($000) $479 Avg Close — Range —
Q3 2022
Shares 68,475 Value ($000) $493 Avg Close — Range —
Q2 2022
Shares 101,575 Value ($000) $864 Avg Close — Range —
Q1 2022
Shares 114,175 Value ($000) $1,024 Avg Close — Range —
Q4 2021
Shares 107,775 Value ($000) $1,493 Avg Close — Range —
Q3 2021
Shares 41,675 Value ($000) $445 Avg Close — Range —
Q2 2021
Shares 69,175 Value ($000) $623 Avg Close — Range —
Q1 2021
Shares 125,975 Value ($000) $1,335 Avg Close — Range —
Q4 2020
Shares 102,775 Value ($000) $1,295 Avg Close — Range —
Q3 2020
Shares 73,475 Value ($000) $646 Avg Close — Range —