AMGEN INC

Ticker: AMGN CUSIP: 031162100 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,192,290 Value ($000) $390,248 Avg Close $315.95 Range $281.00 - $346.38

Q3 2025

Shares 931,756 Value ($000) $262,942 Avg Close $286.59 Range $267.86 - $306.59

Q2 2025

Shares 1,005,582 Value ($000) $280,769 Avg Close $277.77 Range $255.23 - $307.44

Q1 2025

Shares 1,065,694 Value ($000) $332,017 Avg Close $287.24 Range $248.95 - $327.92

Q4 2024

Shares 465,598 Value ($000) $121,353 Avg Close $286.05 Range $245.31 - $316.26

Q3 2024

Shares 493,110 Value ($000) $158,885 Avg Close $313.17 Range $292.07 - $330.95

Q2 2024

Shares 508,931 Value ($000) $159,015 Avg Close $279.32 Range $246.97 - $311.17

Q1 2024

Shares 524,258 Value ($000) $149,056 Avg Close $276.08 Range $254.07 - $309.96

Q4 2023

Shares 586,841 Value ($000) $169,022 Avg Close $255.10 Range $232.90 - $271.72

Q3 2023

Shares 592,985 Value ($000) $159,371 Avg Close $231.86 Range $202.11 - $255.21

Q2 2023

Shares 546,594 Value ($000) $121,355 Avg Close $213.65 Range $195.88 - $235.05

Q1 2023

Shares 538,403 Value ($000) $130,159 Avg Close $224.03 Range $206.60 - $251.53

Q4 2022

Shares 546,603 Value ($000) $143,621 Avg Close $242.73 Range $204.31 - $267.70

Q3 2022

Shares 576,436 Value ($000) $130,329 Avg Close $217.87 Range $201.50 - $227.98

Q2 2022

Shares 586,621 Value ($000) $143,002 Avg Close $218.58 Range $201.93 - $231.00

Q1 2022

Shares 658,194 Value ($000) $159,276 Avg Close $203.29 Range $190.45 - $218.06

Q4 2021

Shares 531,798 Value ($000) $119,639 Avg Close $185.15 Range $174.95 - $203.49

Q3 2021

Shares 612,614 Value ($000) $126,793 Avg Close $200.25 Range $184.86 - $217.02

Q2 2021

Shares 661,392 Value ($000) $161,213 Avg Close $212.50 Range $198.84 - $224.64

Q1 2021

Shares 707,474 Value ($000) $176,026 Avg Close $204.69 Range $189.57 - $236.38

Q4 2020

Shares 670,963 Value ($000) $154,269 Avg Close $196.32 Range $178.44 - $219.36

Q3 2020

Shares 1,102,569 Value ($000) $280,230 Avg Close $209.54 Range $196.05 - $223.35

Q2 2020

Shares 1,185,210 Value ($000) $274,448 Avg Close $191.68 Range $162.60 - $206.00

Q1 2020

Shares 995,607 Value ($000) $201,840 Avg Close $182.24 Range $148.24 - $202.72

Q4 2019

Shares 1,631,872 Value ($000) $393,395 Avg Close $182.69 Range $155.91 - $203.67

Q3 2019

Shares 1,853,972 Value ($000) $361,412 Avg Close $158.01 Range $141.97 - $174.23

Q2 2019

Shares 1,917,750 Value ($000) $353,403 Avg Close $146.19 Range $135.21 - $160.07

Q1 2019

Shares 2,060,111 Value ($000) $391,381 Avg Close $154.67 Range $144.94 - $164.86

Q4 2018

Shares 2,118,695 Value ($000) $412,446 Avg Close $156.83 Range $143.85 - $168.62

Q3 2018

Shares 1,186,819 Value ($000) $246,016 Avg Close $157.37 Range $145.39 - $168.41

Q2 2018

Shares 2,092,670 Value ($000) $386,286 Avg Close $140.24 Range $128.97 - $149.68

Q1 2018

Shares 2,321,644 Value ($000) $395,793 Avg Close $144.43 Range $131.87 - $157.72

Q4 2017

Shares 2,729,941 Value ($000) $474,737 Avg Close $138.21 Range $131.02 - $147.91

Q3 2017

Shares 3,752,219 Value ($000) $699,601 Avg Close $137.50 Range $129.63 - $148.76

Q2 2017

Shares 3,968,892 Value ($000) $683,562 Avg Close $125.35 Range $117.66 - $135.67

Q1 2017

Shares 3,847,690 Value ($000) $631,290 Avg Close $127.19 Range $112.17 - $141.42

Q4 2016

Shares 3,812,062 Value ($000) $557,363 Avg Close $114.37 Range $101.21 - $127.75

Q3 2016

Shares 3,903,671 Value ($000) $651,171 Avg Close $127.72 Range $114.64 - $133.93

Q2 2016

Shares 3,942,644 Value ($000) $599,873 Avg Close $116.70 Range $108.29 - $123.20

Q1 2016

Shares 3,433,014 Value ($000) $513,165 Avg Close $110.79 Range $103.99 - $119.01

Q4 2015

Shares 3,366,407 Value ($000) $546,468 Avg Close $116.50 Range $100.25 - $122.74

Q3 2015

Shares 3,217,534 Value ($000) $445,049 Avg Close $116.24 Range $96.15 - $133.76

Q2 2015

Shares 2,985,401 Value ($000) $458,318 Avg Close $117.59 Range $110.98 - $127.09

Q1 2015

Shares 2,990,553 Value ($000) $478,040 Avg Close $115.04 Range $107.36 - $126.18

Q4 2014

Shares 3,132,962 Value ($000) $499,049 Avg Close $113.30 Range $92.62 - $126.09

Q3 2014

Shares 2,892,880 Value ($000) $406,334 Avg Close $94.52 Range $82.98 - $104.80

Q2 2014

Shares 2,830,090 Value ($000) $334,997 Avg Close $83.37 Range $77.69 - $91.37

Q1 2014

Shares 2,466,253 Value ($000) $304,187 Avg Close $86.89 Range $80.81 - $92.60

Q4 2013

Shares 2,108,737 Value ($000) $240,733 Avg Close $81.11 Range $75.24 - $85.16

Q3 2013

Shares 1,891,534 Value ($000) $211,737 Avg Close $76.98 Range $67.33 - $83.88

Q2 2013

Shares 1,801,509 Value ($000) $177,733 Avg Close $73.34 Range $66.69 - $81.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,192,290	$390,248	$315.95	$281.00 - $346.38
Q3 2025	931,756	$262,942	$286.59	$267.86 - $306.59
Q2 2025	1,005,582	$280,769	$277.77	$255.23 - $307.44
Q1 2025	1,065,694	$332,017	$287.24	$248.95 - $327.92
Q4 2024	465,598	$121,353	$286.05	$245.31 - $316.26
Q3 2024	493,110	$158,885	$313.17	$292.07 - $330.95
Q2 2024	508,931	$159,015	$279.32	$246.97 - $311.17
Q1 2024	524,258	$149,056	$276.08	$254.07 - $309.96
Q4 2023	586,841	$169,022	$255.10	$232.90 - $271.72
Q3 2023	592,985	$159,371	$231.86	$202.11 - $255.21
Q2 2023	546,594	$121,355	$213.65	$195.88 - $235.05
Q1 2023	538,403	$130,159	$224.03	$206.60 - $251.53
Q4 2022	546,603	$143,621	$242.73	$204.31 - $267.70
Q3 2022	576,436	$130,329	$217.87	$201.50 - $227.98
Q2 2022	586,621	$143,002	$218.58	$201.93 - $231.00
Q1 2022	658,194	$159,276	$203.29	$190.45 - $218.06
Q4 2021	531,798	$119,639	$185.15	$174.95 - $203.49
Q3 2021	612,614	$126,793	$200.25	$184.86 - $217.02
Q2 2021	661,392	$161,213	$212.50	$198.84 - $224.64
Q1 2021	707,474	$176,026	$204.69	$189.57 - $236.38
Q4 2020	670,963	$154,269	$196.32	$178.44 - $219.36
Q3 2020	1,102,569	$280,230	$209.54	$196.05 - $223.35
Q2 2020	1,185,210	$274,448	$191.68	$162.60 - $206.00
Q1 2020	995,607	$201,840	$182.24	$148.24 - $202.72
Q4 2019	1,631,872	$393,395	$182.69	$155.91 - $203.67
Q3 2019	1,853,972	$361,412	$158.01	$141.97 - $174.23
Q2 2019	1,917,750	$353,403	$146.19	$135.21 - $160.07
Q1 2019	2,060,111	$391,381	$154.67	$144.94 - $164.86
Q4 2018	2,118,695	$412,446	$156.83	$143.85 - $168.62
Q3 2018	1,186,819	$246,016	$157.37	$145.39 - $168.41
Q2 2018	2,092,670	$386,286	$140.24	$128.97 - $149.68
Q1 2018	2,321,644	$395,793	$144.43	$131.87 - $157.72
Q4 2017	2,729,941	$474,737	$138.21	$131.02 - $147.91
Q3 2017	3,752,219	$699,601	$137.50	$129.63 - $148.76
Q2 2017	3,968,892	$683,562	$125.35	$117.66 - $135.67
Q1 2017	3,847,690	$631,290	$127.19	$112.17 - $141.42
Q4 2016	3,812,062	$557,363	$114.37	$101.21 - $127.75
Q3 2016	3,903,671	$651,171	$127.72	$114.64 - $133.93
Q2 2016	3,942,644	$599,873	$116.70	$108.29 - $123.20
Q1 2016	3,433,014	$513,165	$110.79	$103.99 - $119.01
Q4 2015	3,366,407	$546,468	$116.50	$100.25 - $122.74
Q3 2015	3,217,534	$445,049	$116.24	$96.15 - $133.76
Q2 2015	2,985,401	$458,318	$117.59	$110.98 - $127.09
Q1 2015	2,990,553	$478,040	$115.04	$107.36 - $126.18
Q4 2014	3,132,962	$499,049	$113.30	$92.62 - $126.09
Q3 2014	2,892,880	$406,334	$94.52	$82.98 - $104.80
Q2 2014	2,830,090	$334,997	$83.37	$77.69 - $91.37
Q1 2014	2,466,253	$304,187	$86.89	$80.81 - $92.60
Q4 2013	2,108,737	$240,733	$81.11	$75.24 - $85.16
Q3 2013	1,891,534	$211,737	$76.98	$67.33 - $83.88
Q2 2013	1,801,509	$177,733	$73.34	$66.69 - $81.06