AMGEN INC

Ticker: AMGN CUSIP: 031162100 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 28,977 Value ($000) $9,484 Avg Close $315.95 Range $281.00 - $346.38

Q3 2025

Shares 128,859 Value ($000) $36,364 Avg Close $286.59 Range $267.86 - $306.59

Q2 2025

Shares 625,081 Value ($000) $174,529 Avg Close $277.77 Range $255.23 - $307.44

Q1 2025

Shares 1,260,884 Value ($000) $392,828 Avg Close $287.24 Range $248.95 - $327.92

Q4 2024

Shares 1,974,213 Value ($000) $514,559 Avg Close $286.05 Range $245.31 - $316.26

Q3 2024

Shares 166,446 Value ($000) $53,631 Avg Close $313.17 Range $292.07 - $330.95

Q2 2024

Shares 306,680 Value ($000) $95,822 Avg Close $279.32 Range $246.97 - $311.17

Q1 2024

Shares 413,736 Value ($000) $117,633 Avg Close $276.08 Range $254.07 - $309.96

Q4 2023

Shares 555,752 Value ($000) $160,068 Avg Close $255.10 Range $232.90 - $271.72

Q3 2023

Shares 816,566 Value ($000) $219,460 Avg Close $231.86 Range $202.11 - $255.21

Q2 2023

Shares 780,563 Value ($000) $173,301 Avg Close $213.65 Range $195.88 - $235.05

Q1 2023

Shares 318,234 Value ($000) $76,933 Avg Close $224.03 Range $206.60 - $251.53

Q4 2022

Shares 1,250,125 Value ($000) $328,333 Avg Close $242.73 Range $204.31 - $267.70

Q3 2022

Shares 803,093 Value ($000) $181,017 Avg Close $217.87 Range $201.50 - $227.98

Q2 2022

Shares 971,111 Value ($000) $236,272 Avg Close $218.58 Range $201.93 - $231.00

Q1 2022

Shares 931,096 Value ($000) $225,158 Avg Close $203.29 Range $190.45 - $218.06

Q4 2021

Shares 1,474,514 Value ($000) $331,722 Avg Close $185.15 Range $174.95 - $203.49

Q3 2021

Shares 1,256,070 Value ($000) $267,103 Avg Close $200.25 Range $184.86 - $217.02

Q2 2021

Shares 1,146,422 Value ($000) $279,441 Avg Close $212.50 Range $198.84 - $224.64

Q1 2021

Shares 837,995 Value ($000) $208,502 Avg Close $204.69 Range $189.57 - $236.38

Q4 2020

Shares 172,932 Value ($000) $39,761 Avg Close $196.32 Range $178.44 - $219.36

Q3 2020

Shares 96,571 Value ($000) $24,544 Avg Close $209.54 Range $196.05 - $223.35

Q2 2020

Shares 220,700 Value ($000) $52,054 Avg Close $191.68 Range $162.60 - $206.00

Q1 2020

Shares 931,980 Value ($000) $188,941 Avg Close $182.24 Range $148.24 - $202.72

Q4 2019

Shares 262,158 Value ($000) $63,199 Avg Close $182.69 Range $155.91 - $203.67

Q3 2019

Shares 1,242,920 Value ($000) $240,517 Avg Close $158.01 Range $141.97 - $174.23

Q2 2019

Shares 1,322,331 Value ($000) $243,679 Avg Close $146.19 Range $135.21 - $160.07

Q1 2019

Shares 1,620,496 Value ($000) $307,862 Avg Close $154.67 Range $144.94 - $164.86

Q4 2018

Shares 512,507 Value ($000) $99,769 Avg Close $156.83 Range $143.85 - $168.62

Q3 2018

Shares 507,811 Value ($000) $105,265 Avg Close $157.37 Range $145.39 - $168.41

Q2 2018

Shares 588,567 Value ($000) $108,643 Avg Close $140.24 Range $128.97 - $149.68

Q1 2018

Shares 800,786 Value ($000) $136,518 Avg Close $144.43 Range $131.87 - $157.72

Q4 2017

Shares 2,465,740 Value ($000) $428,792 Avg Close $138.21 Range $131.02 - $147.91

Q3 2017

Shares 1,642,408 Value ($000) $306,227 Avg Close $137.50 Range $129.63 - $148.76

Q2 2017

Shares 2,513,102 Value ($000) $432,831 Avg Close $125.35 Range $117.66 - $135.67

Q1 2017

Shares 1,736,265 Value ($000) $284,869 Avg Close $127.19 Range $112.17 - $141.42

Q4 2016

Shares 1,374,091 Value ($000) $200,906 Avg Close $114.37 Range $101.21 - $127.75

Q3 2016

Shares 383,093 Value ($000) $63,904 Avg Close $127.72 Range $114.64 - $133.93

Q2 2016

Shares 1,669,005 Value ($000) $253,939 Avg Close $116.70 Range $108.29 - $123.20

Q1 2016

Shares 2,973,952 Value ($000) $445,885 Avg Close $110.79 Range $103.99 - $119.01

Q4 2015

Shares 2,527,242 Value ($000) $410,247 Avg Close $116.50 Range $100.25 - $122.74

Q3 2015

Shares 1,426,433 Value ($000) $197,304 Avg Close $116.24 Range $96.15 - $133.76

Q2 2015

Shares 501,170 Value ($000) $76,940 Avg Close $117.59 Range $110.98 - $127.09

Q1 2015

Shares 629,572 Value ($000) $100,637 Avg Close $115.04 Range $107.36 - $126.18

Q4 2014

Shares 926,639 Value ($000) $147,604 Avg Close $113.30 Range $92.62 - $126.09

Q3 2014

Shares 1,290,080 Value ($000) $181,204 Avg Close $94.52 Range $82.98 - $104.80

Q2 2014

Shares 244,731 Value ($000) $28,969 Avg Close $83.37 Range $77.69 - $91.37

Q1 2014

Shares 12,940 Value ($000) $1,596 Avg Close $86.89 Range $80.81 - $92.60

Q4 2013

Shares 492,241 Value ($000) $56,195 Avg Close $81.11 Range $75.24 - $85.16

Q3 2013

Shares 497,899 Value ($000) $55,735 Avg Close $76.98 Range $67.33 - $83.88

Q2 2013

Shares 1,373,609 Value ($000) $135,520 Avg Close $73.34 Range $66.69 - $81.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	28,977	$9,484	$315.95	$281.00 - $346.38
Q3 2025	128,859	$36,364	$286.59	$267.86 - $306.59
Q2 2025	625,081	$174,529	$277.77	$255.23 - $307.44
Q1 2025	1,260,884	$392,828	$287.24	$248.95 - $327.92
Q4 2024	1,974,213	$514,559	$286.05	$245.31 - $316.26
Q3 2024	166,446	$53,631	$313.17	$292.07 - $330.95
Q2 2024	306,680	$95,822	$279.32	$246.97 - $311.17
Q1 2024	413,736	$117,633	$276.08	$254.07 - $309.96
Q4 2023	555,752	$160,068	$255.10	$232.90 - $271.72
Q3 2023	816,566	$219,460	$231.86	$202.11 - $255.21
Q2 2023	780,563	$173,301	$213.65	$195.88 - $235.05
Q1 2023	318,234	$76,933	$224.03	$206.60 - $251.53
Q4 2022	1,250,125	$328,333	$242.73	$204.31 - $267.70
Q3 2022	803,093	$181,017	$217.87	$201.50 - $227.98
Q2 2022	971,111	$236,272	$218.58	$201.93 - $231.00
Q1 2022	931,096	$225,158	$203.29	$190.45 - $218.06
Q4 2021	1,474,514	$331,722	$185.15	$174.95 - $203.49
Q3 2021	1,256,070	$267,103	$200.25	$184.86 - $217.02
Q2 2021	1,146,422	$279,441	$212.50	$198.84 - $224.64
Q1 2021	837,995	$208,502	$204.69	$189.57 - $236.38
Q4 2020	172,932	$39,761	$196.32	$178.44 - $219.36
Q3 2020	96,571	$24,544	$209.54	$196.05 - $223.35
Q2 2020	220,700	$52,054	$191.68	$162.60 - $206.00
Q1 2020	931,980	$188,941	$182.24	$148.24 - $202.72
Q4 2019	262,158	$63,199	$182.69	$155.91 - $203.67
Q3 2019	1,242,920	$240,517	$158.01	$141.97 - $174.23
Q2 2019	1,322,331	$243,679	$146.19	$135.21 - $160.07
Q1 2019	1,620,496	$307,862	$154.67	$144.94 - $164.86
Q4 2018	512,507	$99,769	$156.83	$143.85 - $168.62
Q3 2018	507,811	$105,265	$157.37	$145.39 - $168.41
Q2 2018	588,567	$108,643	$140.24	$128.97 - $149.68
Q1 2018	800,786	$136,518	$144.43	$131.87 - $157.72
Q4 2017	2,465,740	$428,792	$138.21	$131.02 - $147.91
Q3 2017	1,642,408	$306,227	$137.50	$129.63 - $148.76
Q2 2017	2,513,102	$432,831	$125.35	$117.66 - $135.67
Q1 2017	1,736,265	$284,869	$127.19	$112.17 - $141.42
Q4 2016	1,374,091	$200,906	$114.37	$101.21 - $127.75
Q3 2016	383,093	$63,904	$127.72	$114.64 - $133.93
Q2 2016	1,669,005	$253,939	$116.70	$108.29 - $123.20
Q1 2016	2,973,952	$445,885	$110.79	$103.99 - $119.01
Q4 2015	2,527,242	$410,247	$116.50	$100.25 - $122.74
Q3 2015	1,426,433	$197,304	$116.24	$96.15 - $133.76
Q2 2015	501,170	$76,940	$117.59	$110.98 - $127.09
Q1 2015	629,572	$100,637	$115.04	$107.36 - $126.18
Q4 2014	926,639	$147,604	$113.30	$92.62 - $126.09
Q3 2014	1,290,080	$181,204	$94.52	$82.98 - $104.80
Q2 2014	244,731	$28,969	$83.37	$77.69 - $91.37
Q1 2014	12,940	$1,596	$86.89	$80.81 - $92.60
Q4 2013	492,241	$56,195	$81.11	$75.24 - $85.16
Q3 2013	497,899	$55,735	$76.98	$67.33 - $83.88
Q2 2013	1,373,609	$135,520	$73.34	$66.69 - $81.06