AMGEN INC

Ticker: AMGN CUSIP: 031162100 Class: COM

GREAT LAKES ADVISORS, LLC's Holding History (CIK: 0001078013)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 113,971 Value ($000) $37,305 Avg Close $315.95 Range $281.00 - $346.38

Q3 2025

Shares 115,190 Value ($000) $32,507 Avg Close $286.59 Range $267.86 - $306.59

Q2 2025

Shares 117,488 Value ($000) $32,804 Avg Close $277.77 Range $255.23 - $307.44

Q1 2025

Shares 118,529 Value ($000) $36,709 Avg Close $287.24 Range $248.95 - $327.92

Q4 2024

Shares 136,289 Value ($000) $35,522 Avg Close $286.05 Range $245.31 - $316.26

Q3 2024

Shares 319,921 Value ($000) $103,082 Avg Close $313.17 Range $292.07 - $330.95

Q2 2024

Shares 325,093 Value ($000) $101,575 Avg Close $279.32 Range $246.97 - $311.17

Q1 2024

Shares 356,314 Value ($000) $101,307 Avg Close $276.08 Range $254.07 - $309.96

Q4 2023

Shares 331,137 Value ($000) $95,374 Avg Close $255.10 Range $232.90 - $271.72

Q3 2023

Shares 406,488 Value ($000) $109,248 Avg Close $231.86 Range $202.11 - $255.21

Q2 2023

Shares 28,618 Value ($000) $6,354 Avg Close $213.65 Range $195.88 - $235.05

Q1 2023

Shares 30,424 Value ($000) $7,355 Avg Close $224.03 Range $206.60 - $251.53

Q4 2022

Shares 39,894 Value ($000) $1,114 Avg Close $242.73 Range $204.31 - $267.70

Q3 2022

Shares 32,452 Value ($000) $7,315 Avg Close $217.87 Range $201.50 - $227.98

Q2 2022

Shares 39,317 Value ($000) $9,566 Avg Close $218.58 Range $201.93 - $231.00

Q1 2022

Shares 19,856 Value ($000) $4,802 Avg Close $203.29 Range $190.45 - $218.06

Q4 2021

Shares 18,480 Value ($000) $4,158 Avg Close $185.15 Range $174.95 - $203.49

Q3 2021

Shares 17,599 Value ($000) $3,742 Avg Close $200.25 Range $184.86 - $217.02

Q2 2021

Shares 17,688 Value ($000) $4,311 Avg Close $212.50 Range $198.84 - $224.64

Q1 2021

Shares 17,405 Value ($000) $4,330 Avg Close $204.69 Range $189.57 - $236.38

Q4 2020

Shares 17,162 Value ($000) $3,946 Avg Close $196.32 Range $178.44 - $219.36

Q3 2020

Shares 16,454 Value ($000) $4,181 Avg Close $209.54 Range $196.05 - $223.35

Q2 2020

Shares 15,959 Value ($000) $3,763 Avg Close $191.68 Range $162.60 - $206.00

Q1 2020

Shares 16,152 Value ($000) $3,274 Avg Close $182.24 Range $148.24 - $202.72

Q4 2019

Shares 15,669 Value ($000) $3,778 Avg Close $182.69 Range $155.91 - $203.67

Q3 2019

Shares 15,440 Value ($000) $2,988 Avg Close $158.01 Range $141.97 - $174.23

Q2 2019

Shares 15,303 Value ($000) $2,820 Avg Close $146.19 Range $135.21 - $160.07

Q1 2019

Shares 16,282 Value ($000) $3,093 Avg Close $154.67 Range $144.94 - $164.86

Q4 2018

Shares 19,088 Value ($000) $3,717 Avg Close $156.83 Range $143.85 - $168.62

Q3 2018

Shares 18,120 Value ($000) $3,756 Avg Close $157.37 Range $145.39 - $168.41

Q2 2018

Shares 13,401 Value ($000) $2,474 Avg Close $140.24 Range $128.97 - $149.68

Q1 2018

Shares 14,700 Value ($000) $2,506 Avg Close $144.43 Range $131.87 - $157.72

Q4 2017

Shares 325,731 Value ($000) $56,644 Avg Close $138.21 Range $131.02 - $147.91

Q3 2017

Shares 231,658 Value ($000) $43,193 Avg Close $137.50 Range $129.63 - $148.76

Q2 2017

Shares 375,636 Value ($000) $64,696 Avg Close $125.35 Range $117.66 - $135.67

Q1 2017

Shares 387,185 Value ($000) $63,522 Avg Close $127.19 Range $112.17 - $141.42

Q4 2016

Shares 390,720 Value ($000) $57,128 Avg Close $114.37 Range $101.21 - $127.75

Q3 2016

Shares 293,224 Value ($000) $48,912 Avg Close $127.72 Range $114.64 - $133.93

Q2 2016

Shares 297,303 Value ($000) $45,235 Avg Close $116.70 Range $108.29 - $123.20

Q1 2016

Shares 294,302 Value ($000) $44,124 Avg Close $110.79 Range $103.99 - $119.01

Q4 2015

Shares 277,922 Value ($000) $45,116 Avg Close $116.50 Range $100.25 - $122.74

Q3 2015

Shares 285,274 Value ($000) $39,744 Avg Close $116.24 Range $96.15 - $133.76

Q2 2015

Shares 258,589 Value ($000) $39,699 Avg Close $117.59 Range $110.98 - $127.09

Q1 2015

Shares 131,587 Value ($000) $21,036 Avg Close $115.04 Range $107.36 - $126.18

Q4 2014

Shares 5,973 Value ($000) $951 Avg Close $113.30 Range $92.62 - $126.09

Q3 2014

Shares 4,778 Value ($000) $671 Avg Close $94.52 Range $82.98 - $104.80

Q2 2014

Shares 5,256 Value ($000) $622 Avg Close $83.37 Range $77.69 - $91.37

Q1 2014

Shares 5,283 Value ($000) $652 Avg Close $86.89 Range $80.81 - $92.60

Q4 2013

Shares 5,283 Value ($000) $603 Avg Close $81.11 Range $75.24 - $85.16

Q3 2013

Shares 10,604 Value ($000) $1,187 Avg Close $76.98 Range $67.33 - $83.88

Q2 2013

Shares 10,604 Value ($000) $1,047 Avg Close $73.34 Range $66.69 - $81.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	113,971	$37,305	$315.95	$281.00 - $346.38
Q3 2025	115,190	$32,507	$286.59	$267.86 - $306.59
Q2 2025	117,488	$32,804	$277.77	$255.23 - $307.44
Q1 2025	118,529	$36,709	$287.24	$248.95 - $327.92
Q4 2024	136,289	$35,522	$286.05	$245.31 - $316.26
Q3 2024	319,921	$103,082	$313.17	$292.07 - $330.95
Q2 2024	325,093	$101,575	$279.32	$246.97 - $311.17
Q1 2024	356,314	$101,307	$276.08	$254.07 - $309.96
Q4 2023	331,137	$95,374	$255.10	$232.90 - $271.72
Q3 2023	406,488	$109,248	$231.86	$202.11 - $255.21
Q2 2023	28,618	$6,354	$213.65	$195.88 - $235.05
Q1 2023	30,424	$7,355	$224.03	$206.60 - $251.53
Q4 2022	39,894	$1,114	$242.73	$204.31 - $267.70
Q3 2022	32,452	$7,315	$217.87	$201.50 - $227.98
Q2 2022	39,317	$9,566	$218.58	$201.93 - $231.00
Q1 2022	19,856	$4,802	$203.29	$190.45 - $218.06
Q4 2021	18,480	$4,158	$185.15	$174.95 - $203.49
Q3 2021	17,599	$3,742	$200.25	$184.86 - $217.02
Q2 2021	17,688	$4,311	$212.50	$198.84 - $224.64
Q1 2021	17,405	$4,330	$204.69	$189.57 - $236.38
Q4 2020	17,162	$3,946	$196.32	$178.44 - $219.36
Q3 2020	16,454	$4,181	$209.54	$196.05 - $223.35
Q2 2020	15,959	$3,763	$191.68	$162.60 - $206.00
Q1 2020	16,152	$3,274	$182.24	$148.24 - $202.72
Q4 2019	15,669	$3,778	$182.69	$155.91 - $203.67
Q3 2019	15,440	$2,988	$158.01	$141.97 - $174.23
Q2 2019	15,303	$2,820	$146.19	$135.21 - $160.07
Q1 2019	16,282	$3,093	$154.67	$144.94 - $164.86
Q4 2018	19,088	$3,717	$156.83	$143.85 - $168.62
Q3 2018	18,120	$3,756	$157.37	$145.39 - $168.41
Q2 2018	13,401	$2,474	$140.24	$128.97 - $149.68
Q1 2018	14,700	$2,506	$144.43	$131.87 - $157.72
Q4 2017	325,731	$56,644	$138.21	$131.02 - $147.91
Q3 2017	231,658	$43,193	$137.50	$129.63 - $148.76
Q2 2017	375,636	$64,696	$125.35	$117.66 - $135.67
Q1 2017	387,185	$63,522	$127.19	$112.17 - $141.42
Q4 2016	390,720	$57,128	$114.37	$101.21 - $127.75
Q3 2016	293,224	$48,912	$127.72	$114.64 - $133.93
Q2 2016	297,303	$45,235	$116.70	$108.29 - $123.20
Q1 2016	294,302	$44,124	$110.79	$103.99 - $119.01
Q4 2015	277,922	$45,116	$116.50	$100.25 - $122.74
Q3 2015	285,274	$39,744	$116.24	$96.15 - $133.76
Q2 2015	258,589	$39,699	$117.59	$110.98 - $127.09
Q1 2015	131,587	$21,036	$115.04	$107.36 - $126.18
Q4 2014	5,973	$951	$113.30	$92.62 - $126.09
Q3 2014	4,778	$671	$94.52	$82.98 - $104.80
Q2 2014	5,256	$622	$83.37	$77.69 - $91.37
Q1 2014	5,283	$652	$86.89	$80.81 - $92.60
Q4 2013	5,283	$603	$81.11	$75.24 - $85.16
Q3 2013	10,604	$1,187	$76.98	$67.33 - $83.88
Q2 2013	10,604	$1,047	$73.34	$66.69 - $81.06