AMGEN INC

Ticker: AMGN CUSIP: 031162100 Class: COM

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 98,852 Value ($000) $32,355 Avg Close $315.95 Range $281.00 - $346.38

Q1 2025

Shares 178,257 Value ($000) $55,536 Avg Close $287.24 Range $248.95 - $327.92

Q4 2024

Shares 6,071 Value ($000) $1,582 Avg Close $286.05 Range $245.31 - $316.26

Q3 2024

Shares 705,111 Value ($000) $227,194 Avg Close $313.17 Range $292.07 - $330.95

Q2 2024

Shares 656,498 Value ($000) $205,123 Avg Close $279.32 Range $246.97 - $311.17

Q1 2024

Shares 483,440 Value ($000) $137,452 Avg Close $276.08 Range $254.07 - $309.96

Q4 2023

Shares 137,041 Value ($000) $39,471 Avg Close $255.10 Range $232.90 - $271.72

Q3 2023

Shares 1,548,228 Value ($000) $416,102 Avg Close $231.86 Range $202.11 - $255.21

Q2 2023

Shares 215,997 Value ($000) $47,956 Avg Close $213.65 Range $195.88 - $235.05

Q1 2023

Shares 143,731 Value ($000) $34,747 Avg Close $224.03 Range $206.60 - $251.53

Q4 2022

Shares 59,351 Value ($000) $15,588 Avg Close $242.73 Range $204.31 - $267.70

Q3 2022

Shares 79,564 Value ($000) $17,933 Avg Close $217.87 Range $201.50 - $227.98

Q2 2022

Shares 258,228 Value ($000) $62,827 Avg Close $218.58 Range $201.93 - $231.00

Q1 2022

Shares 319,930 Value ($000) $77,365 Avg Close $203.29 Range $190.45 - $218.06

Q4 2021

Shares 104,915 Value ($000) $23,602 Avg Close $185.15 Range $174.95 - $203.49

Q3 2021

Shares 2,849 Value ($000) $606 Avg Close $200.25 Range $184.86 - $217.02

Q2 2021

Shares 42,869 Value ($000) $10,449 Avg Close $212.50 Range $198.84 - $224.64

Q1 2021

Shares 62,425 Value ($000) $15,533 Avg Close $204.69 Range $189.57 - $236.38

Q4 2020

Shares 11,376 Value ($000) $2,616 Avg Close $196.32 Range $178.44 - $219.36

Q3 2020

Shares 5,690 Value ($000) $1,446 Avg Close $209.54 Range $196.05 - $223.35

Q2 2020

Shares 71,595 Value ($000) $16,886 Avg Close $191.68 Range $162.60 - $206.00

Q1 2020

Shares 4,953 Value ($000) $1,004 Avg Close $182.24 Range $148.24 - $202.72

Q3 2019

Shares 723 Value ($000) $140 Avg Close $158.01 Range $141.97 - $174.23

Q2 2019

Shares 25,924 Value ($000) $4,777 Avg Close $146.19 Range $135.21 - $160.07

Q1 2017

Shares 5,178 Value ($000) $849 Avg Close $127.19 Range $112.17 - $141.42

Q4 2016

Shares 174,660 Value ($000) $25,537 Avg Close $114.37 Range $101.21 - $127.75

Q3 2016

Shares 37,857 Value ($000) $6,315 Avg Close $127.72 Range $114.64 - $133.93

Q2 2016

Shares 88,742 Value ($000) $13,502 Avg Close $116.70 Range $108.29 - $123.20

Q1 2016

Shares 8,712 Value ($000) $1,306 Avg Close $110.79 Range $103.99 - $119.01

Q4 2015

Shares 412,300 Value ($000) $66,929 Avg Close $116.50 Range $100.25 - $122.74

Q3 2015

Shares 4,301 Value ($000) $595 Avg Close $116.24 Range $96.15 - $133.76

Q2 2015

Shares 55,277 Value ($000) $8,486 Avg Close $117.59 Range $110.98 - $127.09

Q4 2014

Shares 62,593 Value ($000) $9,970 Avg Close $113.30 Range $92.62 - $126.09

Q3 2014

Shares 262,519 Value ($000) $36,873 Avg Close $94.52 Range $82.98 - $104.80

Q2 2014

Shares 71,966 Value ($000) $8,519 Avg Close $83.37 Range $77.69 - $91.37

Q2 2013

Shares 2,200 Value ($000) $217 Avg Close $73.34 Range $66.69 - $81.06

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	98,852	$32,355	$315.95	$281.00 - $346.38
Q1 2025	178,257	$55,536	$287.24	$248.95 - $327.92
Q4 2024	6,071	$1,582	$286.05	$245.31 - $316.26
Q3 2024	705,111	$227,194	$313.17	$292.07 - $330.95
Q2 2024	656,498	$205,123	$279.32	$246.97 - $311.17
Q1 2024	483,440	$137,452	$276.08	$254.07 - $309.96
Q4 2023	137,041	$39,471	$255.10	$232.90 - $271.72
Q3 2023	1,548,228	$416,102	$231.86	$202.11 - $255.21
Q2 2023	215,997	$47,956	$213.65	$195.88 - $235.05
Q1 2023	143,731	$34,747	$224.03	$206.60 - $251.53
Q4 2022	59,351	$15,588	$242.73	$204.31 - $267.70
Q3 2022	79,564	$17,933	$217.87	$201.50 - $227.98
Q2 2022	258,228	$62,827	$218.58	$201.93 - $231.00
Q1 2022	319,930	$77,365	$203.29	$190.45 - $218.06
Q4 2021	104,915	$23,602	$185.15	$174.95 - $203.49
Q3 2021	2,849	$606	$200.25	$184.86 - $217.02
Q2 2021	42,869	$10,449	$212.50	$198.84 - $224.64
Q1 2021	62,425	$15,533	$204.69	$189.57 - $236.38
Q4 2020	11,376	$2,616	$196.32	$178.44 - $219.36
Q3 2020	5,690	$1,446	$209.54	$196.05 - $223.35
Q2 2020	71,595	$16,886	$191.68	$162.60 - $206.00
Q1 2020	4,953	$1,004	$182.24	$148.24 - $202.72
Q3 2019	723	$140	$158.01	$141.97 - $174.23
Q2 2019	25,924	$4,777	$146.19	$135.21 - $160.07
Q1 2017	5,178	$849	$127.19	$112.17 - $141.42
Q4 2016	174,660	$25,537	$114.37	$101.21 - $127.75
Q3 2016	37,857	$6,315	$127.72	$114.64 - $133.93
Q2 2016	88,742	$13,502	$116.70	$108.29 - $123.20
Q1 2016	8,712	$1,306	$110.79	$103.99 - $119.01
Q4 2015	412,300	$66,929	$116.50	$100.25 - $122.74
Q3 2015	4,301	$595	$116.24	$96.15 - $133.76
Q2 2015	55,277	$8,486	$117.59	$110.98 - $127.09
Q4 2014	62,593	$9,970	$113.30	$92.62 - $126.09
Q3 2014	262,519	$36,873	$94.52	$82.98 - $104.80
Q2 2014	71,966	$8,519	$83.37	$77.69 - $91.37
Q2 2013	2,200	$217	$73.34	$66.69 - $81.06