AMGEN INC

Ticker: AMGN CUSIP: 031162100 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2025

Shares 992 Value ($000) $309 Avg Close $287.24 Range $248.95 - $327.92

Q4 2024

Shares 2,693 Value ($000) $702 Avg Close $286.05 Range $245.31 - $316.26

Q3 2024

Shares 13,476 Value ($000) $4,342 Avg Close $313.17 Range $292.07 - $330.95

Q4 2023

Shares 32,000 Value ($000) $9,217 Avg Close $255.10 Range $232.90 - $271.72

Q3 2023

Shares 1,180 Value ($000) $317 Avg Close $231.86 Range $202.11 - $255.21

Q2 2023

Shares 5,025 Value ($000) $1,116 Avg Close $213.65 Range $195.88 - $235.05

Q1 2023

Shares 890 Value ($000) $215 Avg Close $224.03 Range $206.60 - $251.53

Q3 2022

Shares 2,603 Value ($000) $587 Avg Close $217.87 Range $201.50 - $227.98

Q2 2022

Shares 2,368 Value ($000) $576 Avg Close $218.58 Range $201.93 - $231.00

Q1 2022

Shares 11,067 Value ($000) $2,676 Avg Close $203.29 Range $190.45 - $218.06

Q4 2021

Shares 1,199 Value ($000) $270 Avg Close $185.15 Range $174.95 - $203.49

Q1 2021

Shares 823 Value ($000) $205 Avg Close $204.69 Range $189.57 - $236.38

Q4 2019

Shares 966 Value ($000) $233 Avg Close $182.69 Range $155.91 - $203.67

Q2 2019

Shares 3,682 Value ($000) $679 Avg Close $146.19 Range $135.21 - $160.07

Q1 2019

Shares 5,548 Value ($000) $1,054 Avg Close $154.67 Range $144.94 - $164.86

Q4 2018

Shares 16,171 Value ($000) $3,148 Avg Close $156.83 Range $143.85 - $168.62

Q3 2018

Shares 1,584 Value ($000) $328 Avg Close $157.37 Range $145.39 - $168.41

Q2 2018

Shares 11,311 Value ($000) $2,088 Avg Close $140.24 Range $128.97 - $149.68

Q1 2018

Shares 34,964 Value ($000) $5,961 Avg Close $144.43 Range $131.87 - $157.72

Q2 2017

Shares 1,730 Value ($000) $298 Avg Close $125.35 Range $117.66 - $135.67

Q1 2017

Shares 1,571 Value ($000) $258 Avg Close $127.19 Range $112.17 - $141.42

Q4 2016

Shares 1,941 Value ($000) $284 Avg Close $114.37 Range $101.21 - $127.75

Q3 2016

Shares 5,775 Value ($000) $963 Avg Close $127.72 Range $114.64 - $133.93

Q4 2015

Shares 2,041 Value ($000) $331 Avg Close $116.50 Range $100.25 - $122.74

Q3 2015

Shares 1,530 Value ($000) $212 Avg Close $116.24 Range $96.15 - $133.76

Q2 2015

Shares 1,718 Value ($000) $264 Avg Close $117.59 Range $110.98 - $127.09

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2025	992	$309	$287.24	$248.95 - $327.92
Q4 2024	2,693	$702	$286.05	$245.31 - $316.26
Q3 2024	13,476	$4,342	$313.17	$292.07 - $330.95
Q4 2023	32,000	$9,217	$255.10	$232.90 - $271.72
Q3 2023	1,180	$317	$231.86	$202.11 - $255.21
Q2 2023	5,025	$1,116	$213.65	$195.88 - $235.05
Q1 2023	890	$215	$224.03	$206.60 - $251.53
Q3 2022	2,603	$587	$217.87	$201.50 - $227.98
Q2 2022	2,368	$576	$218.58	$201.93 - $231.00
Q1 2022	11,067	$2,676	$203.29	$190.45 - $218.06
Q4 2021	1,199	$270	$185.15	$174.95 - $203.49
Q1 2021	823	$205	$204.69	$189.57 - $236.38
Q4 2019	966	$233	$182.69	$155.91 - $203.67
Q2 2019	3,682	$679	$146.19	$135.21 - $160.07
Q1 2019	5,548	$1,054	$154.67	$144.94 - $164.86
Q4 2018	16,171	$3,148	$156.83	$143.85 - $168.62
Q3 2018	1,584	$328	$157.37	$145.39 - $168.41
Q2 2018	11,311	$2,088	$140.24	$128.97 - $149.68
Q1 2018	34,964	$5,961	$144.43	$131.87 - $157.72
Q2 2017	1,730	$298	$125.35	$117.66 - $135.67
Q1 2017	1,571	$258	$127.19	$112.17 - $141.42
Q4 2016	1,941	$284	$114.37	$101.21 - $127.75
Q3 2016	5,775	$963	$127.72	$114.64 - $133.93
Q4 2015	2,041	$331	$116.50	$100.25 - $122.74
Q3 2015	1,530	$212	$116.24	$96.15 - $133.76
Q2 2015	1,718	$264	$117.59	$110.98 - $127.09