AMPHASTAR PHARMACEUTICALS IN

Ticker: AMPH CUSIP: 03209R103 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 557,066 Value ($000) $14,918 Avg Close $25.76 Range $22.94 - $29.00

Q3 2025

Shares 517,222 Value ($000) $13,784 Avg Close $25.82 Range $20.39 - $31.26

Q2 2025

Shares 293,928 Value ($000) $6,749 Avg Close $24.82 Range $22.64 - $29.27

Q1 2025

Shares 29,188 Value ($000) $846 Avg Close $31.94 Range $25.89 - $39.01

Q4 2024

Shares 118,851 Value ($000) $4,413 Avg Close $45.73 Range $36.48 - $53.96

Q3 2024

Shares 23,659 Value ($000) $1,148 Avg Close $43.89 Range $36.56 - $50.62

Q4 2023

Shares 77,080 Value ($000) $4,767 Avg Close $52.53 Range $43.79 - $63.67

Q3 2023

Shares 100,173 Value ($000) $4,607 Avg Close $54.55 Range $44.86 - $67.66

Q2 2023

Shares 123,599 Value ($000) $7,103 Avg Close $44.33 Range $35.62 - $58.70

Q1 2023

Shares 137,313 Value ($000) $5,149 Avg Close $32.78 Range $27.58 - $38.22

Q4 2022

Shares 57,948 Value ($000) $1,624 Avg Close $29.04 Range $26.76 - $31.64

Q3 2022

Shares 57,879 Value ($000) $1,626 Avg Close $32.65 Range $27.10 - $39.07

Q2 2022

Shares 61,735 Value ($000) $2,148 Avg Close $35.69 Range $28.64 - $44.46

Q1 2022

Shares 65,139 Value ($000) $2,338 Avg Close $28.36 Range $22.07 - $37.16

Q4 2021

Shares 26,769 Value ($000) $623 Avg Close $20.45 Range $18.12 - $23.85

Q2 2021

Shares 35,699 Value ($000) $720 Avg Close $18.84 Range $16.91 - $20.94

Q1 2021

Shares 17,778 Value ($000) $326 Avg Close $18.59 Range $17.11 - $20.93

Q4 2020

Shares 12,887 Value ($000) $259 Avg Close $19.46 Range $17.51 - $21.38

Q2 2016

Shares 14,208 Value ($000) $229 Avg Close $14.11 Range $11.41 - $16.78

Q1 2016

Shares 22,501 Value ($000) $270 Avg Close $11.79 Range $10.50 - $14.18

Q4 2015

Shares 101,475 Value ($000) $1,444 Avg Close $13.21 Range $10.57 - $15.84

Q3 2015

Shares 17,322 Value ($000) $202 Avg Close $15.00 Range $10.61 - $18.30

Q2 2015

Shares 31,432 Value ($000) $553 Avg Close $15.59 Range $13.55 - $18.25

Q1 2015

Shares 35,902 Value ($000) $537 Avg Close $13.37 Range $11.12 - $15.79

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	557,066	$14,918	$25.76	$22.94 - $29.00
Q3 2025	517,222	$13,784	$25.82	$20.39 - $31.26
Q2 2025	293,928	$6,749	$24.82	$22.64 - $29.27
Q1 2025	29,188	$846	$31.94	$25.89 - $39.01
Q4 2024	118,851	$4,413	$45.73	$36.48 - $53.96
Q3 2024	23,659	$1,148	$43.89	$36.56 - $50.62
Q4 2023	77,080	$4,767	$52.53	$43.79 - $63.67
Q3 2023	100,173	$4,607	$54.55	$44.86 - $67.66
Q2 2023	123,599	$7,103	$44.33	$35.62 - $58.70
Q1 2023	137,313	$5,149	$32.78	$27.58 - $38.22
Q4 2022	57,948	$1,624	$29.04	$26.76 - $31.64
Q3 2022	57,879	$1,626	$32.65	$27.10 - $39.07
Q2 2022	61,735	$2,148	$35.69	$28.64 - $44.46
Q1 2022	65,139	$2,338	$28.36	$22.07 - $37.16
Q4 2021	26,769	$623	$20.45	$18.12 - $23.85
Q2 2021	35,699	$720	$18.84	$16.91 - $20.94
Q1 2021	17,778	$326	$18.59	$17.11 - $20.93
Q4 2020	12,887	$259	$19.46	$17.51 - $21.38
Q2 2016	14,208	$229	$14.11	$11.41 - $16.78
Q1 2016	22,501	$270	$11.79	$10.50 - $14.18
Q4 2015	101,475	$1,444	$13.21	$10.57 - $15.84
Q3 2015	17,322	$202	$15.00	$10.61 - $18.30
Q2 2015	31,432	$553	$15.59	$13.55 - $18.25
Q1 2015	35,902	$537	$13.37	$11.12 - $15.79