AMPIO PHARMACEUTICALS INC

CUSIP: 03209T109 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 27,364 Value ($000) $2 Avg Close — Range —
Q2 2022
Shares 49,822 Value ($000) $8 Avg Close — Range —
Q4 2021
Shares 25,292 Value ($000) $14 Avg Close — Range —
Q3 2020
Shares 12,149 Value ($000) $12 Avg Close — Range —
Q1 2018
Shares 10,518 Value ($000) $36 Avg Close — Range —