ANTHERA PHARMACEUTICALS INC

CUSIP: 03674U201 Class: Common equity shares

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 1,579 Value ($000) $1 Avg Close — Range —
Q4 2016
Shares 1,579 Value ($000) $1 Avg Close — Range —
Q3 2016
Shares 13,310 Value ($000) $42 Avg Close — Range —
Q2 2016
Shares 1,579 Value ($000) $5 Avg Close — Range —
Q1 2016
Shares 27,995 Value ($000) $98 Avg Close — Range —
Q4 2015
Shares 24,867 Value ($000) $115 Avg Close — Range —
Q3 2015
Shares 24,867 Value ($000) $151 Avg Close — Range —
Q2 2015
Shares 23,054 Value ($000) $199 Avg Close — Range —
Q1 2015
Shares 2,446 Value ($000) $11 Avg Close — Range —
Q4 2014
Shares 2,446 Value ($000) $4 Avg Close — Range —
Q3 2014
Shares 2,446 Value ($000) $5 Avg Close — Range —
Q2 2014
Shares 121 Value ($000) $0 Avg Close — Range —
Q1 2014
Shares 121 Value ($000) $0 Avg Close — Range —
Q4 2013
Shares 121 Value ($000) $0 Avg Close — Range —
Q3 2013
Shares 121 Value ($000) $0 Avg Close — Range —