APRICUS BIOSCIENCES INC

CUSIP: 03832V109 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 4,142 Value ($000) $1 Avg Close — Range —
Q2 2016
Shares 4,142 Value ($000) $2 Avg Close — Range —
Q1 2016
Shares 4,142 Value ($000) $3 Avg Close — Range —
Q4 2015
Shares 4,142 Value ($000) $4 Avg Close — Range —
Q3 2015
Shares 4,142 Value ($000) $6 Avg Close — Range —
Q2 2015
Shares 4,142 Value ($000) $7 Avg Close — Range —
Q1 2015
Shares 4,142 Value ($000) $8 Avg Close — Range —
Q4 2014
Shares 4,142 Value ($000) $4 Avg Close — Range —
Q3 2014
Shares 4,142 Value ($000) $6 Avg Close — Range —
Q2 2014
Shares 1,364 Value ($000) $3 Avg Close — Range —
Q1 2014
Shares 1,364 Value ($000) $3 Avg Close — Range —
Q4 2013
Shares 775 Value ($000) $2 Avg Close — Range —
Q3 2013
Shares 775 Value ($000) $2 Avg Close — Range —
Q2 2013
Shares 775 Value ($000) $2 Avg Close — Range —