APTOSE BIOSCIENCES INC

CUSIP: 03835T200 Class: Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 258,311 Value ($000) $359 Avg Close — Range —
Q3 2016
Shares 404,211 Value ($000) $909 Avg Close — Range —
Q1 2016
Shares 33,397 Value ($000) $100 Avg Close — Range —
Q4 2015
Shares 33,397 Value ($000) $84 Avg Close — Range —
Q3 2015
Shares 33,397 Value ($000) $144 Avg Close — Range —
Q2 2015
Shares 33,397 Value ($000) $170 Avg Close — Range —
Q1 2015
Shares 33,397 Value ($000) $181 Avg Close — Range —
Q4 2014
Shares 479,164 Value ($000) $2,833 Avg Close — Range —