APTOSE BIOSCIENCES INC

CUSIP: 03835T200 Class: Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 18,658 Value ($000) $11 Avg Close — Range —
Q2 2022
Shares 34,510 Value ($000) $26 Avg Close — Range —
Q1 2021
Shares 12,142 Value ($000) $73 Avg Close — Range —
Q1 2019
Shares 12,396 Value ($000) $25 Avg Close — Range —
Q4 2016
Shares 17,000 Value ($000) $24 Avg Close — Range —