APREA THERAPEUTICS INC

CUSIP: 03836J102 Class: Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2022
Shares 16,843 Value ($000) $11 Avg Close — Range —
Q2 2022
Shares 60,383 Value ($000) $45 Avg Close — Range —
Q1 2022
Shares 18,610 Value ($000) $35 Avg Close — Range —
Q1 2021
Shares 323,362 Value ($000) $1,649 Avg Close — Range —
Q4 2020
Shares 158,814 Value ($000) $781 Avg Close — Range —