APTINYX INC

CUSIP: 03836N103 Class: COM

Itau Unibanco Holding S.A.'s Holding History (CIK: 0001132597)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 1,958 Value ($000) $57 Avg Close — Range —
Q2 2018
Shares 423 Value ($000) $40 Avg Close — Range —