APTINYX INC

CUSIP: 03836N103 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 365,018 Value ($000) $6,037 Avg Close — Range —
Q3 2018
Shares 465,018 Value ($000) $13,467 Avg Close — Range —
Q2 2018
Shares 565,018 Value ($000) $13,656 Avg Close — Range —