ARENA PHARMACEUTICALS INC

CUSIP: 040047102 Class: COMMON STOCK

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 199,831 Value ($000) $292 Avg Close — Range —
Q4 2016
Shares 176,930 Value ($000) $251 Avg Close — Range —
Q3 2016
Shares 171,913 Value ($000) $301 Avg Close — Range —
Q2 2016
Shares 171,502 Value ($000) $293 Avg Close — Range —
Q1 2016
Shares 162,197 Value ($000) $310 Avg Close — Range —
Q4 2015
Shares 159,487 Value ($000) $303 Avg Close — Range —
Q3 2015
Shares 157,694 Value ($000) $302 Avg Close — Range —
Q2 2015
Shares 152,491 Value ($000) $707 Avg Close — Range —
Q1 2015
Shares 158,962 Value ($000) $694 Avg Close — Range —
Q4 2014
Shares 140,395 Value ($000) $487 Avg Close — Range —
Q3 2014
Shares 143,104 Value ($000) $600 Avg Close — Range —
Q2 2014
Shares 140,135 Value ($000) $821 Avg Close — Range —
Q1 2014
Shares 165,281 Value ($000) $1,041 Avg Close — Range —
Q4 2013
Shares 165,502 Value ($000) $969 Avg Close — Range —
Q3 2013
Shares 167,332 Value ($000) $882 Avg Close — Range —
Q2 2013
Shares 174,094 Value ($000) $1,341 Avg Close — Range —