ARGOS THERAPEUTICS INC

CUSIP: 040221103 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 18,885 Value ($000) $3 Avg Close — Range —
Q3 2017
Shares 11,868 Value ($000) $2 Avg Close — Range —