ARQULE INC

CUSIP: 04269E107 Class: Common Stock

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 1,699 Value ($000) $5 Avg Close — Range —
Q1 2017
Shares 500,000 Value ($000) $530 Avg Close — Range —
Q4 2016
Shares 731,880 Value ($000) $922 Avg Close — Range —
Q3 2016
Shares 731,880 Value ($000) $1,310 Avg Close — Range —
Q2 2016
Shares 750,500 Value ($000) $1,426 Avg Close — Range —
Q1 2016
Shares 802,200 Value ($000) $1,284 Avg Close — Range —
Q4 2015
Shares 945,353 Value ($000) $2,051 Avg Close — Range —
Q3 2015
Shares 959,601 Value ($000) $1,794 Avg Close — Range —
Q2 2015
Shares 995,177 Value ($000) $1,592 Avg Close — Range —
Q1 2015
Shares 670,600 Value ($000) $1,502 Avg Close — Range —
Q4 2014
Shares 1,503,938 Value ($000) $1,835 Avg Close — Range —
Q3 2014
Shares 1,523,005 Value ($000) $1,706 Avg Close — Range —
Q2 2014
Shares 1,343,907 Value ($000) $2,083 Avg Close — Range —
Q1 2014
Shares 904,877 Value ($000) $1,855 Avg Close — Range —
Q4 2013
Shares 605,130 Value ($000) $1,301 Avg Close — Range —
Q3 2013
Shares 550,600 Value ($000) $1,283 Avg Close — Range —
Q2 2013
Shares 3,394,757 Value ($000) $7,876 Avg Close — Range —