ARQULE INC

CUSIP: 04269E107 Class: Common Stock

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q3 2013
Shares 2,500 Value ($000) $5 Avg Close — Range —
Q2 2013
Shares 2,500 Value ($000) $6 Avg Close — Range —