ARQULE INC

CUSIP: 04269E107 Class: Common Stock

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 2,100,000 Value ($000) $10,059 Avg Close — Range —
Q4 2018
Shares 1,066,000 Value ($000) $2,953 Avg Close — Range —