ARQULE INC

CUSIP: 04269E107 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 71,800 Value ($000) $1,433 Avg Close — Range —
Q3 2019
Shares 94,100 Value ($000) $675 Avg Close — Range —
Q3 2016
Shares 47,800 Value ($000) $86 Avg Close — Range —
Q2 2016
Shares 61,800 Value ($000) $117 Avg Close — Range —
Q1 2016
Shares 68,500 Value ($000) $110 Avg Close — Range —
Q4 2015
Shares 97,900 Value ($000) $212 Avg Close — Range —
Q3 2015
Shares 105,802 Value ($000) $197 Avg Close — Range —
Q2 2015
Shares 116,801 Value ($000) $187 Avg Close — Range —
Q1 2015
Shares 116,800 Value ($000) $262 Avg Close — Range —
Q4 2014
Shares 110,400 Value ($000) $135 Avg Close — Range —
Q3 2014
Shares 120,400 Value ($000) $135 Avg Close — Range —
Q2 2014
Shares 144,600 Value ($000) $224 Avg Close — Range —
Q1 2014
Shares 13,700 Value ($000) $28 Avg Close — Range —
Q3 2013
Shares 11,100 Value ($000) $26 Avg Close — Range —
Q2 2013
Shares 14,100 Value ($000) $32 Avg Close — Range —