ASTRAZENECA PLC

Ticker: AZN CUSIP: 046353108 Class: SPONSORED ADR

Darwin Global Management, Ltd.'s Holding History (CIK: 0001839209)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022

Shares 2,849,109 Value ($000) $188,241 Avg Close — Range —

Q1 2022

Shares 1,661,684 Value ($000) $110,236 Avg Close — Range —

Q4 2021

Shares 511,908 Value ($000) $29,819 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2022	2,849,109	$188,241	—	—
Q1 2022	1,661,684	$110,236	—	—
Q4 2021	511,908	$29,819	—	—