AVALANCHE BIOTECHNOLOGIES IN

CUSIP: 05337G107 Class: COM

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 3,852,871 Value ($000) $19,919 Avg Close — Range —
Q4 2015
Shares 3,858,999 Value ($000) $36,738 Avg Close — Range —
Q3 2015
Shares 3,846,483 Value ($000) $31,695 Avg Close — Range —
Q2 2015
Shares 3,824,438 Value ($000) $62,109 Avg Close — Range —
Q1 2015
Shares 3,670,276 Value ($000) $148,720 Avg Close — Range —
Q4 2014
Shares 3,369,245 Value ($000) $181,939 Avg Close — Range —
Q3 2014
Shares 3,337,292 Value ($000) $114,102 Avg Close — Range —