AVALANCHE BIOTECHNOLOGIES IN

CUSIP: 05337G107 Class: COM

PRIMECAP MANAGEMENT CO/CA/'s Holding History (CIK: 0000763212)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 427,000 Value ($000) $2,208 Avg Close — Range —
Q4 2015
Shares 377,800 Value ($000) $3,597 Avg Close — Range —
Q3 2015
Shares 372,400 Value ($000) $3,069 Avg Close — Range —
Q2 2015
Shares 68,300 Value ($000) $1,109 Avg Close — Range —
Q1 2015
Shares 19,300 Value ($000) $782 Avg Close — Range —
Q4 2014
Shares 38,000 Value ($000) $2,052 Avg Close — Range —
Q3 2014
Shares 45,900 Value ($000) $1,569 Avg Close — Range —