AVALANCHE BIOTECHNOLOGIES IN

CUSIP: 05337G107 Class: COM

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 649,550 Value ($000) $35,076 Avg Close — Range —
Q3 2014
Shares 731,208 Value ($000) $25,000 Avg Close — Range —