AVEDRO INC

CUSIP: 05355N109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019
Shares 42,874 Value ($000) $842 Avg Close — Range —
Q1 2019
Shares 30,738 Value ($000) $377 Avg Close — Range —