BIOMARIN PHARMACEUTICAL INC

Ticker: BMRN CUSIP: 09061G101 Class: EQTY

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,004,029 Value ($000) $59,669 Avg Close $54.44 Range $50.76 - $63.89

Q3 2025

Shares 275,238 Value ($000) $14,907 Avg Close $57.19 Range $52.48 - $63.97

Q2 2025

Shares 1,115,428 Value ($000) $61,315 Avg Close $58.89 Range $52.93 - $70.63

Q1 2025

Shares 545,775 Value ($000) $38,581 Avg Close $67.28 Range $60.63 - $73.51

Q4 2024

Shares 275,452 Value ($000) $18,105 Avg Close $66.98 Range $61.15 - $70.98

Q3 2024

Shares 163,348 Value ($000) $11,482 Avg Close $83.59 Range $67.75 - $94.85

Q2 2024

Shares 268,374 Value ($000) $22,095 Avg Close $83.25 Range $73.68 - $93.36

Q1 2024

Shares 422,298 Value ($000) $36,884 Avg Close $89.52 Range $83.44 - $99.25

Q4 2023

Shares 192,452 Value ($000) $18,556 Avg Close $88.47 Range $76.02 - $99.56

Q3 2023

Shares 524,139 Value ($000) $46,376 Avg Close $88.98 Range $83.85 - $95.13

Q2 2023

Shares 909,817 Value ($000) $78,863 Avg Close $94.11 Range $85.66 - $100.38

Q1 2023

Shares 1,131,039 Value ($000) $109,982 Avg Close $103.67 Range $87.34 - $117.77

Q4 2022

Shares 1,409,124 Value ($000) $145,830 Avg Close $93.88 Range $80.53 - $109.56

Q3 2022

Shares 1,019,257 Value ($000) $86,403 Avg Close $89.04 Range $81.66 - $97.76

Q2 2022

Shares 1,048,517 Value ($000) $86,891 Avg Close $79.62 Range $70.73 - $86.98

Q1 2022

Shares 688,106 Value ($000) $53,053 Avg Close $83.67 Range $72.00 - $94.20

Q4 2021

Shares 921,722 Value ($000) $81,435 Avg Close $82.51 Range $71.59 - $92.17

Q3 2021

Shares 775,612 Value ($000) $59,947 Avg Close $78.90 Range $73.95 - $85.74

Q2 2021

Shares 520,881 Value ($000) $43,462 Avg Close $79.27 Range $74.43 - $86.33

Q1 2021

Shares 578,486 Value ($000) $43,681 Avg Close $81.69 Range $72.77 - $92.20

Q4 2020

Shares 588,561 Value ($000) $51,611 Avg Close $79.28 Range $71.65 - $92.57

Q3 2020

Shares 61,330 Value ($000) $4,666 Avg Close $101.18 Range $71.35 - $131.95

Q2 2020

Shares 4,526 Value ($000) $558 Avg Close $99.39 Range $78.77 - $124.95

Q1 2020

Shares 97,485 Value ($000) $8,238 Avg Close $86.16 Range $68.25 - $97.10

Q4 2019

Shares 276,088 Value ($000) $23,343 Avg Close $75.53 Range $62.88 - $86.50

Q3 2019

Shares 143,101 Value ($000) $9,645 Avg Close $77.02 Range $67.24 - $86.99

Q2 2019

Shares 86,435 Value ($000) $7,403 Avg Close $85.55 Range $79.79 - $94.00

Q1 2019

Shares 112,270 Value ($000) $9,973 Avg Close $92.68 Range $82.01 - $100.13

Q4 2018

Shares 235,769 Value ($000) $20,076 Avg Close $95.13 Range $79.13 - $106.74

Q3 2018

Shares 98,211 Value ($000) $9,524 Avg Close $99.82 Range $92.77 - $106.20

Q2 2018

Shares 16,644 Value ($000) $1,568 Avg Close $87.57 Range $75.81 - $99.76

Q1 2018

Shares 85,710 Value ($000) $6,948 Avg Close $85.82 Range $77.05 - $93.44

Q4 2017

Shares 163,674 Value ($000) $14,595 Avg Close $86.95 Range $80.10 - $96.05

Q3 2017

Shares 91,792 Value ($000) $8,543 Avg Close $88.36 Range $80.29 - $95.45

Q2 2017

Shares 14,666 Value ($000) $1,332 Avg Close $90.98 Range $85.45 - $100.51

Q1 2017

Shares 3,000 Value ($000) $263 Avg Close $88.96 Range $82.57 - $95.79

Q3 2016

Shares 86,759 Value ($000) $8,027 Avg Close $94.17 Range $77.04 - $102.49

Q2 2016

Shares 134,179 Value ($000) $10,439 Avg Close $85.01 Range $73.45 - $94.08

Q1 2016

Shares 228,272 Value ($000) $18,828 Avg Close $81.36 Range $62.12 - $105.61

Q4 2015

Shares 398,094 Value ($000) $41,704 Avg Close $104.32 Range $91.21 - $118.48

Q3 2015

Shares 457,441 Value ($000) $48,178 Avg Close $133.58 Range $95.09 - $151.75

Q2 2015

Shares 641,836 Value ($000) $87,790 Avg Close $123.92 Range $110.50 - $141.51

Q1 2015

Shares 453,809 Value ($000) $56,554 Avg Close $105.95 Range $88.51 - $133.54

Q4 2014

Shares 161,109 Value ($000) $14,564 Avg Close $83.16 Range $65.91 - $96.36

Q3 2014

Shares 251,107 Value ($000) $18,120 Avg Close $65.72 Range $55.36 - $73.35

Q2 2014

Shares 115,969 Value ($000) $7,215 Avg Close $60.41 Range $55.04 - $70.42

Q1 2014

Shares 9,341 Value ($000) $637 Avg Close $73.70 Range $64.61 - $84.25

Q4 2013

Shares 24,603 Value ($000) $1,729 Avg Close $67.90 Range $58.65 - $76.02

Q3 2013

Shares 590,508 Value ($000) $42,647 Avg Close $66.46 Range $56.31 - $80.67

Q2 2013

Shares 1,079,906 Value ($000) $60,248 Avg Close $62.32 Range $53.53 - $71.56

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,004,029	$59,669	$54.44	$50.76 - $63.89
Q3 2025	275,238	$14,907	$57.19	$52.48 - $63.97
Q2 2025	1,115,428	$61,315	$58.89	$52.93 - $70.63
Q1 2025	545,775	$38,581	$67.28	$60.63 - $73.51
Q4 2024	275,452	$18,105	$66.98	$61.15 - $70.98
Q3 2024	163,348	$11,482	$83.59	$67.75 - $94.85
Q2 2024	268,374	$22,095	$83.25	$73.68 - $93.36
Q1 2024	422,298	$36,884	$89.52	$83.44 - $99.25
Q4 2023	192,452	$18,556	$88.47	$76.02 - $99.56
Q3 2023	524,139	$46,376	$88.98	$83.85 - $95.13
Q2 2023	909,817	$78,863	$94.11	$85.66 - $100.38
Q1 2023	1,131,039	$109,982	$103.67	$87.34 - $117.77
Q4 2022	1,409,124	$145,830	$93.88	$80.53 - $109.56
Q3 2022	1,019,257	$86,403	$89.04	$81.66 - $97.76
Q2 2022	1,048,517	$86,891	$79.62	$70.73 - $86.98
Q1 2022	688,106	$53,053	$83.67	$72.00 - $94.20
Q4 2021	921,722	$81,435	$82.51	$71.59 - $92.17
Q3 2021	775,612	$59,947	$78.90	$73.95 - $85.74
Q2 2021	520,881	$43,462	$79.27	$74.43 - $86.33
Q1 2021	578,486	$43,681	$81.69	$72.77 - $92.20
Q4 2020	588,561	$51,611	$79.28	$71.65 - $92.57
Q3 2020	61,330	$4,666	$101.18	$71.35 - $131.95
Q2 2020	4,526	$558	$99.39	$78.77 - $124.95
Q1 2020	97,485	$8,238	$86.16	$68.25 - $97.10
Q4 2019	276,088	$23,343	$75.53	$62.88 - $86.50
Q3 2019	143,101	$9,645	$77.02	$67.24 - $86.99
Q2 2019	86,435	$7,403	$85.55	$79.79 - $94.00
Q1 2019	112,270	$9,973	$92.68	$82.01 - $100.13
Q4 2018	235,769	$20,076	$95.13	$79.13 - $106.74
Q3 2018	98,211	$9,524	$99.82	$92.77 - $106.20
Q2 2018	16,644	$1,568	$87.57	$75.81 - $99.76
Q1 2018	85,710	$6,948	$85.82	$77.05 - $93.44
Q4 2017	163,674	$14,595	$86.95	$80.10 - $96.05
Q3 2017	91,792	$8,543	$88.36	$80.29 - $95.45
Q2 2017	14,666	$1,332	$90.98	$85.45 - $100.51
Q1 2017	3,000	$263	$88.96	$82.57 - $95.79
Q3 2016	86,759	$8,027	$94.17	$77.04 - $102.49
Q2 2016	134,179	$10,439	$85.01	$73.45 - $94.08
Q1 2016	228,272	$18,828	$81.36	$62.12 - $105.61
Q4 2015	398,094	$41,704	$104.32	$91.21 - $118.48
Q3 2015	457,441	$48,178	$133.58	$95.09 - $151.75
Q2 2015	641,836	$87,790	$123.92	$110.50 - $141.51
Q1 2015	453,809	$56,554	$105.95	$88.51 - $133.54
Q4 2014	161,109	$14,564	$83.16	$65.91 - $96.36
Q3 2014	251,107	$18,120	$65.72	$55.36 - $73.35
Q2 2014	115,969	$7,215	$60.41	$55.04 - $70.42
Q1 2014	9,341	$637	$73.70	$64.61 - $84.25
Q4 2013	24,603	$1,729	$67.90	$58.65 - $76.02
Q3 2013	590,508	$42,647	$66.46	$56.31 - $80.67
Q2 2013	1,079,906	$60,248	$62.32	$53.53 - $71.56