BIOMARIN PHARMACEUTICAL INC

Ticker: BMRN CUSIP: 09061G101 Class: EQTY

Main Street Research LLC's Holding History (CIK: 0001513211)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015

Shares 44,426 Value ($000) $4,654 Avg Close $104.32 Range $91.21 - $118.48

Q3 2015

Shares 45,171 Value ($000) $5,287 Avg Close $133.58 Range $95.09 - $151.75

Q2 2015

Shares 87,357 Value ($000) $11,949 Avg Close $123.92 Range $110.50 - $141.51

Q1 2015

Shares 85,694 Value ($000) $10,679 Avg Close $105.95 Range $88.51 - $133.54

Q4 2014

Shares 83,909 Value ($000) $7,585 Avg Close $83.16 Range $65.91 - $96.36

Q3 2014

Shares 81,239 Value ($000) $5,862 Avg Close $65.72 Range $55.36 - $73.35

Q2 2014

Shares 75,724 Value ($000) $4,711 Avg Close $60.41 Range $55.04 - $70.42

Q1 2014

Shares 72,799 Value ($000) $4,966 Avg Close $73.70 Range $64.61 - $84.25

Q4 2013

Shares 60,375 Value ($000) $4,247 Avg Close $67.90 Range $58.65 - $76.02

Q3 2013

Shares 58,848 Value ($000) $4,247 Avg Close $66.46 Range $56.31 - $80.67

Q2 2013

Shares 50,935 Value ($000) $2,839 Avg Close $62.32 Range $53.53 - $71.56

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2015	44,426	$4,654	$104.32	$91.21 - $118.48
Q3 2015	45,171	$5,287	$133.58	$95.09 - $151.75
Q2 2015	87,357	$11,949	$123.92	$110.50 - $141.51
Q1 2015	85,694	$10,679	$105.95	$88.51 - $133.54
Q4 2014	83,909	$7,585	$83.16	$65.91 - $96.36
Q3 2014	81,239	$5,862	$65.72	$55.36 - $73.35
Q2 2014	75,724	$4,711	$60.41	$55.04 - $70.42
Q1 2014	72,799	$4,966	$73.70	$64.61 - $84.25
Q4 2013	60,375	$4,247	$67.90	$58.65 - $76.02
Q3 2013	58,848	$4,247	$66.46	$56.31 - $80.67
Q2 2013	50,935	$2,839	$62.32	$53.53 - $71.56